Results 181 to 190 of about 16,097 (238)

On the photoproduction of DNA/RNA cyclobutane pyrimidine dimers

Theoretical Chemistry Accounts, 2010
The UV photoreactivity of different pyrimidine DNA/RNA nucleobases along the singlet manifold leading to the formation of cyclobutane pyrimidine dimers has been studied by using the CASPT2 level of theory. The initially irradiated singlet state promotes the formation of excimers between pairs of properly oriented nucleobases through the overlap between
Daniel Roca-Sanjuán, TERESA Climent, Juan JOSÉ Serrano-Pérez   +2 more
exaly   +4 more sources

Biological consequences of cyclobutane pyrimidine dimers

Journal of Photochemistry and Photobiology B: Biology, 2001
In the skin many molecules may absorb ultraviolet (UV) radiation upon exposure. In particular, cellular DNA strongly absorbs shorter wavelength solar UV radiation, resulting in various types of DNA damage. Among the DNA photoproducts produced the cyclobutane pyrimidine dimers (CPDs) are predominant.
Vink, A.A., Roza, L.
openaire   +4 more sources

Photorepair of ultraviolet radiation-induced pyrimidine dimers in corneal DNA

Mutation Research - DNA Repair Reports, 1988
The induction and photorepair of pyrimidine dimers in DNA have been measured in the ultraviolet-irradiated, corneal epithelium of the marsupial, Monodelphis domestica, using damage-specific nucleases from Micrococcus luteus in conjunction with agarose ...
Ronald D Ley, Lee A Applegate, S E Freeman   +2 more
exaly   +2 more sources

Ultraviolet radiation-induced lethality and repair of pyrimidine dimers in fish embryos

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1988
Pimephales promelas (fathead minnow) embryos were used to show a correlation between induction of pyrimidine dimers in DNA and embryo death. Embryo killing was measured by a lack of heart-beat and blood circulation at 48 h post-ultraviolet radiation (UVR)
Lee A Applegate, Ronald D Ley
exaly   +1 more source

Computational Reference Data for the Photochemistry of Cyclobutane Pyrimidine Dimers [PDF]

ChemPhysChem, 2014
The cis–syn cyclobutane pyrimidine dimer is one of the major classes of carcinogenic UV-induced DNA photoproducts. In this work, diverse high-level quantum-chemical methods were used to determine the spectroscopic properties of neutral (singlet and ...
Mario Barbatti
exaly   +2 more sources

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PHOTOSENSITIZED SPLITTING OF PYRIMIDINE DIMERS

Photochemistry and Photobiology, 1970
Abstract— The photosensitized monomerization of cis‐syn and trans‐syn cyclobutane‐type thymine dimers, and the cis‐syn thymine‐uracil dimer, using anthraquinone derivatives as sensitizers, is described.
E, Ben-Hur, I, Rosenthal
openaire   +2 more sources

UV-induced pyrimidine dimers and rosacea

British Journal of Dermatology, 1981
info:eu-repo/semantics ...
Nunzi, Enrico, Rebora, Alfredo, Cornelis, Jan, Cormane, Rudy R.H.   +3 more
openaire   +3 more sources

PYRIMIDINE DIMER FORMATION IN HUMAN SKIN

Photochemistry and Photobiology, 1987
AbstractCyclobutyl pyrimidine dimers are major photoproducts formed upon irradiation of DNA with ultraviolet light. We have developed a method for detecting as few as one pyrimidine dimer per million bases in about 50 ng of non‐radioactive DNA, and have used this method to quantitate dimer yields in human skin DNA exposed in situ to UV.
S E, Freeman, R W, Gange, J C, Sutherland, B M, Sutherland   +3 more
openaire   +2 more sources

Pyrimidine dimers in ultraviolet-irradiated DNA's

Journal of Molecular Biology, 1966
DNA's of various compositions, labeled with radioactive cytosine or thymine, were irradiated with monochromatic ultraviolet light and analyzed by photochemical and chromatographic techniques for photoproducts. The dimers T T ⌢ ,† C T ⌢ and C C ⌢ were identified as primary photochemical products, and U T
R B, Setlow, W L, Carrier
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Photomonomerization of pyrimidine dimers by indoles and proteins

Journal of Theoretical Biology, 1976
Abstract Model systems for the study of photoreactivation have been developed that utilize a variety of indole derivatives. These systems can split uracil cis-syn cyclobutadipyrimidine, either free or in RNA, when irradiated at wave-lengths absorbed only by the indole moiety. The ability of indole compounds to split dimers is closely related to their
J, Chen, C W, Huang, L, Hinman, M P, Gordon, D A, Deranleau   +4 more
openaire   +2 more sources