Results 11 to 20 of about 15,307 (218)
Perspectives on Cyclobutane Pyrimidine Dimers—Rise of the Dark Dimers† [PDF]
Photochemistry and Photobiology, 2021 ABSTRACTSome early reports demonstrate that levels of cyclobutane pyrimidine dimers (CPD) may increase after UVR exposure had ended, although these observations were treated as artifacts. More recently, it has been shown unequivocally that CPD formation does occur post‐irradiation, with maximal levels occurring after about 2–3 h.
Karl Lawrence +4 more
openalex +4 more sources
DNA backbone conformation in cis–syn pyrimidine[]pyrimidine cyclobutane dimers [PDF]
Biopolymers, 1980 A theoretical calculation involving minimization of energy functions was made to determine the conformation of a deoxydinucleoside monophosphate pyrimidine[ ]pyrimidine cis-syn cyclobutane dimer. Such single-stranded moieties are useful models for the in uiuo situation because single strands are more easily damaged, and the damage inhibits the normal ...
Suse Broyde +2 more
+5 more sources
UVA generates pyrimidine dimers in DNA directly. [PDF]
Biophys J, 2009 There is increasing evidence that UVA radiation, which makes up approximately 95% of the solar UV light reaching the Earth's surface and is also commonly used for cosmetic purposes, is genotoxic. However, in contrast to UVC and UVB, the mechanisms by which UVA produces various DNA lesions are still unclear.
Jiang Y +7 more
europepmc +5 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2017 The title compounds, C16H15N5OS, (I), and C12H12FN5OS, (II), are [(diaminopyrimidine)sulfanyl]acetamide derivatives. In (I), the pyrimidine ring is inclined to the naphthalene ring system by 55.5 (1)°, while in (II), the pyrimidine ring is inclined to ...
S. Subasri +5 more
doaj +1 more source
Crystal structure of (2-methyl-4-phenyl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-3-yl)(phenyl)methanone
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C24H18N2OS, the pyrimidine ring has a flat envelope conformation with the methine C atom as the flap. The attached phenyl and benzoyl rings are inclined to the mean plane of the pyrimidine ring by 84.87 (8) and 75.33 (9 ...
T. Sankar +3 more
doaj +1 more source
Taq DNA polymerase blockage at pyrimidine dimers [PDF]
Nucleic Acids Research, 1996 Nucleic Acids Research, 24 (8)
Wellinger, Ralf-Erik, Thoma, Fritz
openaire +4 more sources
4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
Acta Crystallographica Section E, 2013 The title compound, C10H16N4, crystalizes with two molecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in
S. Sreenivasa +5 more
doaj +1 more source
Angewandte Chemie, EarlyView.Photocatalytic cross‐coupling: A redox‐neutral photochemical method enables direct C(sp2)─C(sp2) bond formation between phenols and heteroaryl halides using an organic dye and base. Complementary radical generation allows efficient cross‐coupling in up to 91% yield. Mechanistic studies, DFT, HTE, and machine learning rationalize and predict reactivity,
Matthew C. Carson +4 more
wiley +2 more sources
Methyl 2-[2-(benzyloxycarbonylamino)propan-2-yl]-5-hydroxy-6-methoxypyrimidine-4-carboxylate
Acta Crystallographica Section E, 2011 In the title compound, C18H21N3O6, a pyrimidine derivative, the dihedral angle between the benzene and pyrimidine rings is 52.26 (12)°.
Hoong-Kun Fun +4 more
doaj +1 more source