Results 51 to 60 of about 15,307 (218)

Ethyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate

open access: yesActa Crystallographica Section E, 2008
There are three formula units in the asymmetric unit of the title compound, C14H16N2O4·H2O. Molecules are linked by N—H...O hydrogen bonds into dimers with the common R22(8) graph-set motif.
T. N. Guru Row   +4 more
doaj   +1 more source

How Plants May Maintain Protein Homeostasis Under Rising Atmospheric CO2

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Vascular plants may employ several physiological mechanisms to stabilize their protein contents as atmospheric CO2 concentrations change over a day, year, decade, or century. One mechanism is that plants may rely more on soil ammonium as their nitrogen source when CO2 increases.
Arnold J. Bloom   +2 more
wiley   +1 more source

4-[(3-Formyl-4-hydroxyphenyl)diazenyl]-N-(pyrimidin-2-yl)benzenesulfonamide

open access: yesActa Crystallographica Section E, 2008
The title molecule, C17H13N5O4S, has a trans configuration with respect to the diazenyl (azo) group. The pyrimidine ring and the terminal benzene ring are inclined at angles of 89.38 (4) and 1.6 (6)°, respectively, with respect to the ...
Ken Sakai   +5 more
doaj   +1 more source

Effects of DNA looping on pyrimidine dimer formation [PDF]

open access: yesNucleic Acids Research, 1992
We have assessed the effects of DNA curvature on pyrimidine dimer (PD) formation by examining the pattern of PD formation in DNA held in a loop by lambda repressor. The loop region was composed of diverse DNA sequences such that potential PD sites occurred throughout the loop.
J R, Pehrson, L H, Cohen
openaire   +2 more sources

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson   +6 more
wiley   +1 more source

Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.
To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara   +3 more
wiley   +1 more source

Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate

open access: yesActa Crystallographica Section E, 2009
In the title compound, C15H18N2O5·H2O, the pyrimidine ring adopts a flattened-boat conformation. The ethoxy group attached to the benzene ring is in an extended conformation.
M. Thenmozhi   +4 more
doaj   +1 more source

Blocking cyclobutane pyrimidine dimer formation by steric hindrance [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2016
Replacement of the C5 thymine methyl group with a bulky tert-butyl substituent completely blocks the formation of CPDs.
Vendrell Criado, Victoria   +4 more
openaire   +4 more sources

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair

open access: yesNature Communications, 2017
UV-induced mutagenic cyclobutane pyrimidine dimers on nucleosomal DNA are sensed by the damage recognition factors DDB2 and XPC via an unknown mechanism. Here, the authors show that the histone methyltransferase ASH1L regulates the DDB2 to XPC handoff by
Chiara Balbo Pogliano   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy