Results 81 to 90 of about 15,307 (218)
Quercetin and Its Nano‐Based Formulations Against Skin Cancer: A Narrative Review
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, chemotherapy, and radiotherapy—often suffer from limitations such as adverse side effects, tumor resistance, and inadequate efficacy.
Mahtab Khanyabzadeh +14 more
wiley +1 more source
Acta Crystallographica Section E, 2009 The dihedral angle between the planes of two aromatic rings in the title compound [systematic name: 3-benzoyl-5-chloro-pyrimidine-2,4(1H,3H)-dione], C11H7ClN2O3, is 86.79 (6)°.
Keith Clinch, Graeme J. Gainsford
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Dynamic accumulation of cyclobutane pyrimidine dimers and its response to changes in DNA conformation. [PDF]
Nucleic Acids Res, 2023 Moirangthem R, Gamage MN, Rokita SE.
europepmc +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.In 2D culture, the cirsimarin (i) decreased cell viability in both assays, (ii) induced apoptosis, (iii) reduced clonogenicity, (iv) prevented cell migration, (v) induced DNA damage, and (vi) negatively modulated gene expression. In the 3D model, reductions in spheroid viability, area, and cell migration were also observed.
Anna Gabriele Prado dos Santos +10 more
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5-Bromo-2-chloropyrimidin-4-amine
Acta Crystallographica Section E, 2013 In the title compound, C4H3BrClN3, the pyrimidine ring is essentially planar (r.m.s. deviation from the plane = 0.087 Å). In the crystal, pairs of N—H...N hydrogen bonds connect the molecules into inversion dimers; these are connected by
Mohan Kumar +6 more
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The Role of Acetyl Zingerone and Its Derivatives in Inhibiting UV-Induced, Incident, and Delayed Cyclobutane Pyrimidine Dimers. [PDF]
Antioxidants (Basel), 2023 Srivastava J +6 more
europepmc +1 more source
The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance
MedComm – Oncology, Volume 5, Issue 1, March 2026.One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang +3 more
wiley +1 more source
N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
Acta Crystallographica Section E, 2010 In the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form a ...
Hao-Fei Qi +3 more
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DNA Containing Cyclobutane Pyrimidine Dimers Is Released from UVB-Irradiated Keratinocytes in a Caspase-Dependent Manner. [PDF]
J Invest Dermatol, 2022 Carpenter MA, Ginugu M, Khan S, Kemp MG.
europepmc +1 more source
Ions as Architects of DNA Nanostructures: Mechanisms, Simulations, and Technological Frontiers
Small Structures, Volume 7, Issue 3, March 2026.Ions are not merely passive electrolytes but active regulators of DNA nanostructures. This review shows how ion valence, hydration, and specificity govern electrostatic screening, correlation, and confinement, enabling DNA origami, metallized DNA, nanopores, hydrogels, DNAzymes, molecular machines, and energy devices through integrated experimental and
Sergiy Perepelytsya +5 more
wiley +1 more source