Results 191 to 200 of about 72,841 (281)

Constitutive nitric oxide synthases deficiency impairs cyclobutane pyrimidine dimer repair following solar UV exposure in cells and mice

Photochemistry and Photobiology, EarlyView.
Proposed model for the dual role of cNOS in DNA damage and repair upon UV radiation. Abstract Solar ultraviolet (sUV) radiation is a major environmental factor that induces DNA damage, promoting skin aging and carcinogenesis. The formation of cyclobutane pyrimidine dimers (CPDs) is one of the most prevalent forms of UV‐induced DNA lesions, playing a ...
Veronica Bahamondes Lorca, Yuxi Zhou, Christina Athans, Hailey Payne, Madison Wright, Zeinab Feyyaz, Lingying Tong, Dawn L. Sammons, Shiyong Wu   +8 more
wiley   +1 more source

A Review of Recent Progress on the Anticancer Activity of Heterocyclic Compounds

SynOpen
Beena Negi, Aarshiya Kwatra
doaj   +1 more source

Magnetic nanocatalyst for microwave-assisted synthesis of Benzo[4,5]imidazo[1,2-<i>a</i>]pyrimidines via A3 coupling. [PDF]

Front Chem
Pan Y.
europepmc   +1 more source

Alloxazine derivatives as multifunctional agents for photodynamic therapy, cancer cell imaging, and cell proliferation inhibition

Photochemistry and Photobiology, EarlyView.
Alloxazine photosensitizers, molecularly engineered through sugar conjugation and methoxy substitution to enhance solubility, photodynamic potency, and fluorescence, enable image‐guided photodynamic therapy while inhibiting cancer cell growth in the absence of photoactivation.
Rubej R. Khan, Sourav Kanti Seth, Reshma Mathew, Nitza V. Falcón‐Cruz, Chris Acquah, Steffen Jockusch, Liraz Levi, Carlos E. Crespo‐Hernández   +7 more
wiley   +1 more source

Multicomponent catalyst-free regioselective synthesis and binding studies of 3-aroyl-2-methylimidazo[1,2-<i>a</i>]pyrimidines with BSA using biophysical and computational techniques. [PDF]

RSC Adv
Aggarwal R, Sharma M, Sumran G, Kumar P.
europepmc   +1 more source

Expression of key enzymes of purine and pyrimidine metabolism in a hepatocyte-derived cell line at different phases of the growth cycle

, 1990
Doris Mayer, Yutaka Natsumeda, Tadashi Ikegami, Mary A. Faderan, May S. Lui, Jahangir Emrani, Melissa A. Reardon, Edith Oláh, George Weber   +8 more
openalex   +2 more sources

Investigation of 222‐nm ultraviolet C irradiation bactericidal effect on the surgical field in a rabbit model

Photochemistry and Photobiology, EarlyView.
In a rabbit surgical field model seeded with polymicrobial flora, a single dose of 222‐nm UV‐C (500 mJ/cm2) markedly reduced bacterial colonies, achieving a bactericidal effect comparable to 254‐nm UV‐C (200 mJ/cm2), while no UV‐C irradiation showed heavy growth. Wound healing did not differ among groups. Microbiota profiling detected SSI‐relevant taxa
Tomoaki Fukui, Yuya Yamamoto, Kyohei Takase, Keisuke Oe, Kenichi Sawauchi, Ryota Nishida, Takahiro Niikura, Rena Kaigome, Masahiro Sasaki, Toru Koi, Hiroyuki Ohashi, Ryosuke Kuroda   +11 more
wiley   +1 more source

Pyrimidine sufficiency is required for Sae two-component system signaling in <i>Staphylococcus aureus</i>. [PDF]

J Bacteriol
DiMaggio DA, Yeo W-S, Brinsmade SR.
europepmc   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

Photochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes, Fernanda M. Prado, Helena C. Junqueira, Marisa H. G. Medeiros, Graziella E Ronsein, Jean Cadet, Paolo Di Mascio   +6 more
wiley   +1 more source

Structural Diversity of Heteroleptic Cobalt(II) Dicyanamide Coordination Polymers with Substituted Pyrazines and Pyrimidines as Auxiliary Ligands. [PDF]

Molecules
Palion-Gazda J, Świtlicka A, Choroba K, Malicka E, Machura B, Trzęsowska-Kruszyńska A.   +5 more
europepmc   +1 more source