Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum [PDF]
Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle.
Annette N. Chiang+48 more
core +3 more sources
Analyzing binary heterocyclic pyrimidinones using density functional theory (DFT) calculations and Monte Carlo (MC) simulations, as well as assessing their ADME (Absorption, Distribution, Metabolism, and Excretion) and toxicological properties is the ...
Ahmed M. Wahba+2 more
doaj +2 more sources
Sulphonated graphene oxide was used for cascade condensation and cyclization reactions towards accessing substituted pyrazolo pyrimidinones. Further, sulphonation and amination reactions were integrated through continuous flow chemistry to access PDE-5 ...
Vinay Kumar Sthalam+4 more
semanticscholar +1 more source
Design and preparation of a new Ni/Arg@zeolite-Y nano-composite: investigation of its performance as a multi-functional and bio-organic catalyst for the one-pot synthesis of thieno[2,3-<i>d</i>]pyrimidinones. [PDF]
Kalhor M, Modares Z, Azizkhani V.
europepmc +2 more sources
ChemInform Abstract: Syntheses and Studies of Metaphase‐Arresting Pyrimidinones. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Tore Benneche+7 more
openaire +4 more sources
Fe3O4@MCM-48–SO3H: An efficient magnetically separable nanocatalyst for the synthesis of benzo[f]chromeno[2,3-d]pyrimidinones [PDF]
H. Kefayati+3 more
semanticscholar +2 more sources
Cu-phthalocyanine Coated Hybrid Magnetic Nanoparticles: Preparation and Application in the Synthesis of Mono- and Bis pyrano[2,3-d]pyrimidinones and mono- and Bis-2-amino-4H-pyrans [PDF]
In this research, Cu-phthalocyanine coated hybrid magnetic nanoparticles have been prepared in a simple method and evaluated as an efficient catalyst in the preparation of mono- and bis-pyrano[2,3-d]pyrimidinones and mono- and bis-2-amino-4H-pyrans from ...
Ali Reza Karimi+2 more
doaj +1 more source
A facile one-pot synthesis of aryl-substituted fused pyrimidinones
H. Lee, Yang-Heon Song
semanticscholar +3 more sources