Results 21 to 30 of about 5,835 (244)

Synthesis of new binary trimethoxyphenylfuran pyrimidinones as proficient and sustainable corrosion inhibitors for carbon steel in acidic medium: experimental, surface morphology analysis, and theoretical studies

BMC Chemistry
In this study, synthesis and assessment of the corrosion inhibition of four new binary heterocyclic pyrimidinones on CS in 1.0 M hydrochloric acid solutions at various temperatures (30–50 °C) were investigated. The synthesized molecules were designed and
Hajar A. Ali, Ahmed. A. El-Hossiany, Ashraf S. Abousalem, Mohamed A. Ismail, Abd El-Aziz S. Fouda, Eslam A. Ghaith   +5 more
doaj   +2 more sources

WELPSA: A natural catalyst of alkali and alkaline earth metals for the facile synthesis of tetrahydrobenzo[b]pyrans and pyrano[2,3‐d]pyrimidinones as inhibitors of SARS‐CoV‐2

Applied organometallic chemistry, 2021
Since 2019, the infection of SARS‐CoV‐2 has been spreading worldwide and caused potentially lethal health problems. In view of this, the present study explores the most commodious and environmentally benign synthetic protocol for the synthesis of ...
A. Nesaragi, R. Kamble, Swati R. Hoolageri, Ahmedraza Mavazzan, Suresh F. Madar, A. Anand, S. Joshi   +6 more
semanticscholar   +1 more source

Molecular Docking and Biophysical Studies for Antiproliferative Assessment of Synthetic Pyrazolo-Pyrimidinones Tethered with Hydrazide-Hydrazones

International Journal of Molecular Sciences, 2021
Chemotherapy represents the most applied approach to cancer treatment. Owing to the frequent onset of chemoresistance and tumor relapses, there is an urgent need to discover novel and more effective anticancer drugs.
Mabrouk Horchani, G. Della Sala, Alessia Caso, Federica D’Aria, Germana Esposito, I. Laurenzana, C. Giancola, V. Costantino, H. Jannet, Anis Romdhane   +9 more
semanticscholar   +1 more source

Sulphonated graphene oxide catalyzed continuous flow synthesis of pyrazolo pyrimidinones, sildenafil and other PDE-5 inhibitors

RSC Advances, 2021
Sulphonated graphene oxide was used for cascade condensation and cyclization reactions towards accessing substituted pyrazolo pyrimidinones. Further, sulphonation and amination reactions were integrated through continuous flow chemistry to access PDE-5 ...
Vinay Kumar Sthalam, B. Mahajan, Purushotham Reddy Karra, Ajay K. Singh, Srihari Pabbaraja   +4 more
semanticscholar   +1 more source

Synthesis of triazole bridged N-glycosides of pyrazolo[1,5-a]pyrimidinones as anticancer agents and their in silico docking studies. [PDF]

RSC Adv
In the pursuit of novel therapeutic agents, we present a comprehensive study on the design, synthesis, and evaluation of a diverse library of triazole bridged N-glycosides of pyrazolo[1,5-a]pyrimidinones, employing a microwave-assisted synthetic approach
Tiwari G, Mishra VK, Kumari P, Khanna A, Sharma S, Sagar R.   +5 more
europepmc   +2 more sources

Syntheses and Studies of Metaphase-Arresting Pyrimidinones. [PDF]

Acta Chemica Scandinavica, 1991
Methods are described for the syntheses of chloromethyl hydroxyalkylphenyl and benzyl ethers, and for the synthesis of bromomethyl phenyl ketone analogs. The hydroxy groups were protected as acetates. The halogenomethyl derivatives have been used for N-alkylation of 5-chloro-2(1H)-pyrimidinone.
Tore Benneche, Gunnar Keilen, Gunnar Hagelin, Reidar Oftebro, Kjell Undheim, Nils Åge Frøystein, George W. Francis, Britt Karlsson   +7 more
openaire   +2 more sources

A green method for the synthesis of isoxazolyl aryl thieno[2,3-d]pyrimidinones using reusable polyethylene glycol as simple solvent catalyst and evaluation of anti-microbial activity [PDF]

, 2022
336-347Novel series of isoxazolyl aryl thieno[2,3-d]pyrimidinones 4 have been synthesized from (E)-2-amino-5-(3-methyl-4- nitroisoxazol-5-yl)-N-(3-methyl-5-styrylisoxazol-4-yl)-4-arylthiophene-3-carboxamide synthon 3. Compound 3 is obtained by reaction
Dharavath, Nagaraju, Malladi, Srinivas Reddy, Saini, Ramakrishna   +2 more
core   +4 more sources

Cu-phthalocyanine Coated Hybrid Magnetic Nanoparticles: Preparation and Application in the Synthesis of Mono- and Bis pyrano[2,3-d]pyrimidinones and mono- and Bis-2-amino-4H-pyrans [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
In this research, Cu-phthalocyanine coated hybrid magnetic nanoparticles have been prepared in a simple method and evaluated as an efficient catalyst in the preparation of mono- and bis-pyrano[2,3-d]pyrimidinones and mono- and bis-2-amino-4H-pyrans from ...
Ali Reza Karimi, Fatemeh Bagherian, Marzie Karimi   +2 more
doaj   +1 more source

Synthesis and Self-Association of 4-Pyrimidinones [PDF]

, 2016
Crystallization of 4-pyrimidinone from CHCl3 produced colorless needles that were shown by X-ray crystallography to consist of cyclic hydrogen-bonded dimers 2 of the 4(3H)-pyrimidinone tautomer 1.
Louis Vaillancourt (3045906), James D. Wuest (1433515), Michel Simard (2483362)   +2 more
core   +1 more source

Microwave-assisted C-5 Iodination of substituted Pyrimidinones and Pirimidine nucleosides [PDF]

, 2003
Direct microwave-assisted iodination of several pyrimidinones and pyrimidine nucleosides with N-iodosuccinimide to give the corresponding 5-iodo derivatives is described.
Lisa Paolini, PETRICCI, ELENA, PAOLINI L, Federico Corelli, CORELLI, FEDERICO, Paolini, L., Elena Petricci, BOTTA, MAURIZIO, Maurizio Botta   +8 more
core   +1 more source