Results 21 to 30 of about 2,340 (179)

Synthesis and Antimicrobial Activity of Some New Pyrimidinone and Oxazinone Derivatives Fused with Thiophene Rings Using 2-Chloro-6-ethoxy-4-acetylpyridine as Starting Material

Molecules, 2012
A series of pyridines, pyrimidinones, oxazinones and their derivatives were synthesized as antimicrobial agents using citrazinic acid (2,6-dihydroxyisonicotinic acid) as a starting material.
Abd El-Galil E. Amr, Aisha S. M. Hossan, Hanaa M. A. Abu-Melha, Mohamed A. Al-Omar   +3 more
doaj   +1 more source

Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

Beilstein Journal of Organic Chemistry, 2018
A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established.
Mark Kelada, John M. D. Walsh, Robert W. Devine, Patrick McArdle, John C. Stephens   +4 more
doaj   +1 more source

Synthesis and Transformations of di-endo-3-Aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic Acid Derivatives

Molecules, 2011
all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13) and all-endo-5-amino-6-(hydroxymethyl)bicyclo[2.2.2]octan-2-ol (10) were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N ...
Márta Palkó, Pál Sohár, Ferenc Fülöp   +2 more
doaj   +1 more source

Quinazolin-4-ones, Thienopyrimidin-4-ones and Related Compounds: New Highly Active Powdery Mildewicides [1]

CHIMIA, 2003
In this short review, new quinazolinones and thieno-pyrimidinones with outstanding powdery mildew activity are introduced. The most important inventions of two major players in this field, DuPont and Syngenta, are presented and interesting ...
Harald Walter, Ronald Zeun
doaj   +1 more source

Prediction and evaluation of pyrimidinones derivatives: DFT analysis, corrosion inhibition, and bioactivity studies

Results in Surfaces and Interfaces
Analyzing binary heterocyclic pyrimidinones using density functional theory (DFT) calculations and Monte Carlo (MC) simulations, as well as assessing their ADME (Absorption, Distribution, Metabolism, and Excretion) and toxicological properties is the ...
Ahmed M. Wahba, Kamel Shoueir, Abd El-Aziz S. Fouda   +2 more
doaj   +1 more source

Synthesis and biological activity of some new fused thieno[2,3-b] pyridine derivatives; pyridothienopyrimidinones and pyridothienotriazinones [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2016
3-Amino-4-aryl-5-ethoxycarbonyl-6-methylthieno[2,3-b]pyrindine-2-carboxamides 3a,b wereprepared and reacted with triethyl orthoformate to give pyridothienopyrimidinone derivatives4a,b.
doaj   +1 more source

A Synthetic Approach to Pyrazolopyranopyrimidinones and Pyrazolopyranooxazinones as Antimicrobial Agents

Journal of Chemistry, 2016
The hitherto unknown 6-amino-4-(2-chloro-5-nitrophenyl)-3-methyl-1,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile 1a was synthesized. Both 1a and its 2,4 dichlorophenyl derivative 1b were utilized as building blocks for the preparation of novel class of ...
A. K. Elziaty, G. Bassioni, A. M. A. Hassan, H. A. Derbala, M. S. Abdel-Aziz   +4 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Syntheses and Studies of Metaphase-Arresting Pyrimidinones. [PDF]

Acta Chemica Scandinavica, 1991
Methods are described for the syntheses of chloromethyl hydroxyalkylphenyl and benzyl ethers, and for the synthesis of bromomethyl phenyl ketone analogs. The hydroxy groups were protected as acetates. The halogenomethyl derivatives have been used for N-alkylation of 5-chloro-2(1H)-pyrimidinone.
Tore Benneche, Gunnar Keilen, Gunnar Hagelin, Reidar Oftebro, Kjell Undheim, Nils Åge Frøystein, George W. Francis, Britt Karlsson   +7 more
openaire   +2 more sources

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

Catalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi, Dina E. Tobbala, Salah M. El-Bahy, Mohamed A. Nassan, Reda S. Salama   +4 more
doaj   +1 more source