Results 11 to 20 of about 3,637 (213)
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compounds 3a, C14H13N5OS, and 3b, C13H12N6OS, both show an E configuration about the N=C bond and a planar NH2 group. The molecules, which only differ in the presence of a phenyl (in 3a) or pyridyl (in 3b) substituent, are closely similar ...
Reham A. Mohamed-Ezzat +2 more
doaj +1 more source
A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV. [PDF]
Arch Pharm (Weinheim)This article presents the latest advances in the development of dihydropyrimidinone (DHPM) derivatives as promising candidates against HIV. By exploring their interactions with essential viral targets and highlighting innovative compounds with potent antiviral activity, we provide an updated perspective on the opportunities for new antiretroviral ...
Leite DI +11 more
europepmc +2 more sources
Syntheses and Studies of Metaphase-Arresting Pyrimidinones. [PDF]
Acta Chemica Scandinavica, 1991 Methods are described for the syntheses of chloromethyl hydroxyalkylphenyl and benzyl ethers, and for the synthesis of bromomethyl phenyl ketone analogs. The hydroxy groups were protected as acetates. The halogenomethyl derivatives have been used for N-alkylation of 5-chloro-2(1H)-pyrimidinone.
Tore Benneche +7 more
openaire +2 more sources
Cu-phthalocyanine Coated Hybrid Magnetic Nanoparticles: Preparation and Application in the Synthesis of Mono- and Bis pyrano[2,3-d]pyrimidinones and mono- and Bis-2-amino-4H-pyrans [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2020 In this research, Cu-phthalocyanine coated hybrid magnetic nanoparticles have been prepared in a simple method and evaluated as an efficient catalyst in the preparation of mono- and bis-pyrano[2,3-d]pyrimidinones and mono- and bis-2-amino-4H-pyrans from ...
Ali Reza Karimi +2 more
doaj +1 more source
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum [PDF]
, 2009 Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle.
Annette N. Chiang +48 more
core +1 more source
Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones [PDF]
, 2009 A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively.
Bernardini, Martina +3 more
core +1 more source
Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis [PDF]
, 2010 Tetrazoles remain a challenge to photochemists. Photolysis leads to cleavage of the tetrazolyl ring, may involve various photodegradation pathways and may produce a diversity of photoproducts, depending on the structure and conformational flexibility of
Amin Ismael +18 more
core +2 more sources
Molecules, 2022 Alteration of insect growth regulators by the action of inhibitors is becoming an attractive strategy to combat disease-transmitting insects. In the present study, we investigated the larvicidal effect of 1,2,3-triazolyl-pyrimidinone derivatives against ...
Katharigatta N. Venugopala +16 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2018 The syntheses of various pyrimidinones as potentially bioactive products by means of the highly controlled continuous-flow retro-Diels–Alder reaction of condensed pyrimidinone derivatives are presented.
Imane Nekkaa +3 more
doaj +1 more source