Results 31 to 40 of about 11,970 (271)
A study of the variability in the febrile responses of rabbits to endogenous pyrogen
, 1985 The range of body temperature increases elicited by a standard dose of endogenous pyrogen (0.5 ml/kg iv) was examined in a population of 26 male New Zealand White rabbits. Although the mean maximum increase in rectal temperature was 0.88 +/- 0.06 degree
J. T. Stitt
core +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Comparison of febrile responsiveness of rats and rabbits to endogenous pyrogen
, 1985 The fever responses of rats and rabbits were compared in detail using a single common source of semipurified endogenous pyrogen prepared from human monocytes.
S. G. Shimada +2 more
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The effect of bacterial pyrogen on the distribution of intrarenal blood flow [PDF]
, 1979 Hemodynamic and biochemical measurements were made before and 90 min after 50 [mu]g of Pseudomonas-derived pyrogen was infused into nine awake dogs. Six control dogs received no pyrogen.
Martin Lindenauer, S. +1 more
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Advanced Science, EarlyView.Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia +4 more
wiley +1 more source
A New Formulation of 99mTc-Macroagreggated Albumin (MAA) Freeze-dried Kit for Lungs Scintigraphy
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2008 A new formulation of macro aggregated albumin (MAA) to be labeled with 99mTc was prepared by a simple and fast method. The suspension of macroagreggated albumin was prepared by diluting 0.4ml human serum albumin (200mg/ml) with normal saline (sterilized
Alaa K. Jabbar +2 more
doaj +1 more source
Observations on the development of the febrile response to pyrogen in newborn pigs
, 1985 The febrile response of newborn pigs to exogenous pyrogen injection was investigated. Lipopolysacharides (LPS, E coli) were injected intravenously into the superior vena cava of 1-30-day-old piglets.
Pela, I. R. +3 more
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Advanced Science, EarlyView.We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen +18 more
wiley +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2023 Scientific relevance. Currently, only the rabbit pyrogen test is used to test the Vianvac® typhoid Vi polysaccharide vaccine for pyrogenicity. As part of the product specification file, the gel-clot test for bacterial endotoxins (BE) will improve the ...
M. V. Abramtseva +2 more
doaj +1 more source
Interferon Fever: Absence of Human Leukocytic Pyrogen Response to Recombinant α-Interferon
, 1984 A sensitive in vitro assay for generation of human leukocytic pyrogen has been used to study the pathogenesis of fever accompanying administration of human α-interferon.
Samuel K Ackerman +5 more
core +1 more source