Results 51 to 60 of about 101,444 (302)

Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate

open access: yesJournal of Lipid Research, 1969
Several mechanisms that utilize farnesyl pyrophosphate and nerolidyl pyrophosphate as condensing substrates have been postulated for the asymmetric condensation reaction in squalene biosynthesis.
S.S. Sofer, H.C. Rilling
doaj   +1 more source

Silicate-, Magnesium Ion-, and Urea-Induced Prebiotic Phosphorylation of Uridine via Pyrophosphate; Revisiting the Hot Drying Water Pool Scenario

open access: yesLife, 2020
The availability of nucleotides on the early Earth is of great significance for the origin of a self-replicating system capable of undergoing evolution. We hereby report the successful phosphorylation reactions of the nucleoside uridine under heating in ...
Maheen Gull   +3 more
doaj   +1 more source

Pyrophosphate of Iron [PDF]

open access: yesThe Boston Medical and Surgical Journal
n ...
openaire   +2 more sources

Lysosomal diacylglycerol pyrophosphate phosphatase is not essential in Trypanosoma brucei. [PDF]

open access: yes
Mg2+-independent phosphatidic acid phosphatase (PAP2), diacylglycerol pyrophosphate phosphatase 1 (Dpp1) is a membrane-associated enzyme in Saccharomyces cerevisiae.
Annese, Tiziana   +2 more
core   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

open access: yesAdvanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li   +5 more
wiley   +1 more source

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

open access: yesAngewandte Chemie, EarlyView.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero   +7 more
wiley   +2 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Thermal and pH stability of Δ2-isopentenyl pyrophosphate

open access: yesJournal of Lipid Research, 1972
The isoprenoid precursors Δ3-isopentenyl pyrophosphate and γ,γ-dimethylallyl pyrophosphate (Δ2-isopentenyl pyrophosphate) have been separated by thin-layer chromatography.
D.M. Logan
doaj   +1 more source

Alkaline Phosphatases Account for Low Plasma Levels of Inorganic Pyrophosphate in Chronic Kidney Disease

open access: yesFrontiers in Cell and Developmental Biology, 2020
IntroductionPatients on dialysis and kidney transplant recipients (KTR) present the syndrome of mineral and bone disorders (MBD), which share common traits with monogenic calcifying diseases related to disturbances of the purinergic system.
Audrey Laurain   +16 more
doaj   +1 more source

Mathematical Modeling of a Supramolecular Assembly for Pyrophosphate Sensing

open access: yesFrontiers in Chemistry, 2021
The power of sensing molecules is often characterized in part by determining their thermodynamic/dynamic properties, in particular the binding constant of a guest to a host.
Fereshteh Emami   +4 more
doaj   +1 more source

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