Results 241 to 250 of about 77,046 (386)

Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis

, 2016
Ine Jørgensen, Yue Zhang, Bryan A. Krantz, Edward A. Miao   +3 more
openalex   +2 more sources

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Pyroptosis in Alzheimer's Disease: Mechanisms and Therapeutic Potential. [PDF]

Cell Mol Neurobiol
Tang T.
europepmc   +1 more source

Investigating the role of SARM1 in central nervous system

Ibrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang, Yuhang Shi, Jinglei Tian, Liming Tang, Fang Cao   +4 more
wiley   +1 more source

Phosphorylated IRF3 promotes GSDME-mediated pyroptosis through RIPK1/FADD/caspase-8 complex formation during mitotic arrest in ovarian cancer. [PDF]

Cell Commun Signal
Gong W, Zhou D, Xu Q, Wang L, Luo M, Zhang Y, Liao Z, Xiong F, Zhao G, Zhao B, Gao Q, Fang Y.   +11 more
europepmc   +1 more source

NLRP3 and pyroptosis blockers for treating inflammatory diseases.

TIPS - Trends in Pharmacological Sciences, 2022
Rebecca C. Coll, K. Schroder, P. Pelegrín   +2 more
semanticscholar   +1 more source

Role of TREM1 in the sevoflurane‐induced inflammatory activation of microglia in vitro

Ibrain, EarlyView.
Perioperative neurocognitive disorders (PNDs) are one of the most common complications in perioperative patients, and neuroinflammatory reaction mediated by microglia plays a key role in their formation. Triggering receptor expressed on myeloid cells 1 (TREM1) is a key regulator of inflammation.
Chunchun Tang, Yuhang Zhu, Dexing Liu, Xue Zheng, Junli Jiang, Wanqiu Yu, Yinan Zhang, Dongqin Chen, Zhaoqiong Zhu   +8 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

TMAO Induces Vascular Endothelial Cells Pyroptosis Through TET2-CYTB-ROS Pathway. [PDF]

J Inflamm Res
Xia L, Wang Z, Chen X.
europepmc   +1 more source

Soluble egg antigen of Schistosoma japonicum induces pyroptosis in hepatic stellate cells by modulating ROS production [PDF]

, 2019
Delong Kong, Fanyun Kong, Xiangye Liu, Chao Yan, Jie Cui, Renxian Tang, Kuiyang Zheng   +6 more
openalex   +1 more source