Results 251 to 260 of about 82,547 (381)

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis [PDF]

, 2020
Susanne Gaul, Aleksandra Leszczynska, Fernando Alegre, Benedikt Kaufmann, Casey D. Johnson, Leon A. Adams, Alexander Wree, Georg Damm, Daniel Seehofer, Carolina Jiménez Calvente, Davide Povero, Tatiana Kisseleva, Akiko Eguchi, Matthew D. McGeough, Hal M. Hoffman, Pablo Pelegrı́n, Ulrich Laufs, Ariel E. Feldstein   +17 more
openalex   +1 more source

Estrogen Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis. [PDF]

Cardiol Res Pract
Cheng J, Li Y, Shen S, Sheng J, Xu B, Wang X, Cheng C, He F.   +7 more
europepmc   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Apoptosis, Autophagy, and Pyroptosis: Immune Escape Strategies for Persistent Infection and Pathogenesis of Classical Swine Fever Virus [PDF]

, 2019
Shengming Ma, Qian Mao, Lin Yi, Mingqiu Zhao, Jinding Chen   +4 more
openalex   +1 more source

Pyroptosis Takes Aim at Neurodevelopment [PDF]

, 2020
Jaeda Coutinho‐Budd, Heather T. Broihier   +1 more
openalex   +1 more source

15-lipoxygenase blockade switches off pan-organ ischaemia-reperfusion injury by inhibiting pyroptosis. [PDF]

Mol Biomed
Li J, Zhang H, Dai M, Huang Y.
europepmc   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Soluble egg antigen of Schistosoma japonicum induces pyroptosis in hepatic stellate cells by modulating ROS production [PDF]

, 2019
Delong Kong, Fanyun Kong, Xiangye Liu, Chao Yan, Jie Cui, Renxian Tang, Kuiyang Zheng   +6 more
openalex   +1 more source

Crocetin curbs radiation induced intestinal injury by blocking KAT2A/NLRP3 succinylation. [PDF]

Sci Rep
Chen H, Wang Y, Xu Y, Liu F, Xu Q, Dong L, Yang C, Xie X, Yang J, Zhang X.   +9 more
europepmc   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source