Results 281 to 290 of about 82,547 (381)

Fyn-T Kinase Regulates DHA-Induced Pyroptosis in Immortalized Normal Human Astrocytes. [PDF]

Cells
Cheng AL, Chai YL, Lee JH, Low CYB, Ong HL, Dawe GS, Arumugam TV, Herr DR, Tan MGK, Lai MKP.   +9 more
europepmc   +1 more source

Effect of peri‐operative pharmacological interventions on postoperative delirium in patients having cardiac surgery: a systematic review and Bayesian network meta‐analysis

Anaesthesia, EarlyView.
Summary Introduction Postoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the ...
Ivo Queiroz, Lucas M. Barbosa, Mariano Gallo Ruelas, Beatriz Araújo, Maria L. R. Defante, Arthur H. Tavares, Cynthia Florencio de Mesquita, Tulio Pimentel, Beatriz Ximenes Mendes, Iuri Ferreira Felix, André Rivera, Rafael Oliva Morgado Ferreira, Helen M. de Oliveira, Bruno B. Righetto, Nathan J. Smischney, Guangyu Tong, Daqing Ma   +16 more
wiley   +1 more source

Naringin inhibits the osteoblast-osteoclast pyroptosis cascade reaction mediated by accumulated bone marrow adipose tissue in the treatment of postmenopausal osteoporosis. [PDF]

J Orthop Translat
Li Z, Gao K, Wang M, Liang S, Li D, Zhang P, Cheng W, Xu Z, Li N.   +8 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Increased HIF-1α in Knee Osteoarthritis Aggravate Synovial Fibrosis via Fibroblast-Like Synoviocyte Pyroptosis

, 2019
Li Zhang, Li Zhang, Zhengquan Huang, Runlin Xing, Xiaochen Li, Songjiang Yin, Jun J. Mao, Li Zhang, Wei Mei, Liang Ding, Peimin Wang   +10 more
openalex   +1 more source

Regulation of pyroptosis by natural products in atherosclerosis: mechanisms and therapeutic potential. [PDF]

Front Pharmacol
Shi N, Wei L, Wang H, Sun S, Yang J, Zhou Y.   +5 more
europepmc   +1 more source

RETRACTION: Long Non‐Coding RNA Sox2OT Promotes Coronary Microembolization‐Induced Myocardial Injury by Mediating Pyroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1527-1527, April 2025.
wiley   +1 more source

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis

Brain Pathology, EarlyView.
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon, Robertas Aleksynas, Marcelina Wojewska, Francesco de Virgiliis, Doron Merkler, Richard Reynolds   +5 more
wiley   +1 more source

Methane alleviates sepsis-induced injury by inhibiting pyroptosis and apoptosis: in vivo and in vitro experiments

, 2019
Zeyu Li, Yifan Jia, Yang Feng, Ruixia Cui, Runchen Miao, Xing Zhang, Kai Qu, Chang Liu, Jingyao Zhang   +8 more
openalex   +1 more source

Activation of cGAS‐STING Pathway by DAI‐Triggered Ferroptosis in CRC Cells Reprograms TAMs Balance to Promote Anti‐Tumor Immunity

Cancer Science, EarlyView.
Our study identified and preliminarily elucidated the ferroptosis‐induced cGAS‐STING‐mediated anti‐tumor pathway triggered by DAI in colorectal cancer cells, providing new insight into the role of PCD in anti‐tumor immunotherapy and screening out potential targets for the treatment of colorectal cancer.
Pengrui Cheng, Que Yang, Xiao Zhang, Qiang Wang, Bingzheng Zhong   +4 more
wiley   +1 more source