Results 291 to 300 of about 77,046 (386)

Identification of pyroptosis related genes and subtypes in atherosclerosis using multiomic and single cell analysis. [PDF]

Sci Rep
Jiang K, He Y, Hu B, Quan L, Peng L, Tian J, Zhou N, Huang E, Zhao Q.   +8 more
europepmc   +1 more source

Increased HIF-1α in Knee Osteoarthritis Aggravate Synovial Fibrosis via Fibroblast-Like Synoviocyte Pyroptosis

, 2019
Li Zhang, Li Zhang, Zhengquan Huang, Runlin Xing, Xiaochen Li, Songjiang Yin, Jun J. Mao, Li Zhang, Wei Mei, Liang Ding, Peimin Wang   +10 more
openalex   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

Aging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda, Yosuke Inaba, Yuki Shiko, Yoshihito Ozawa, Vilhelm A. Bohr, Yoshiro Maezawa, Koutaro Yokote   +15 more
wiley   +1 more source

Activation of pyroptosis impairs basal cell differentiation in the nasal epithelium in chronic rhinosinusitis with nasal polyps. [PDF]

Mol Med Rep
Zhang G, Jin S, Liu J, Du Y, Li Z, Liu L, Xu X, Wang Z, Yan S.   +8 more
europepmc   +1 more source

Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo

, 2020
Zhuang Wang, Zhaoyan Gu, Qing Hou, Weijie Chen, Di Mu, Yuanxing Zhang, Qin Liu, Zhihong Liu, Dahai Yang   +8 more
openalex   +1 more source

Integrative Multiparametric Analysis of Circulating Cell‐Free Nucleic Acids of Plasma in Healthy Individuals During Aging

Aging Cell, EarlyView.
We performed the first integrative multiparametric analysis of plasma circulating cell‐free nucleic acids, including nuclear and mitochondrial DNA, as well as ribosomal, messenger, and micro‐RNAs, in a cohort of 139 healthy individuals. We focused on quantity, integrity, and DNA methylation using assays targeting highly repetitive DNA and highly ...
Nicolas P. Tessier, Lise M. Hardy, Florence Mauger, Antoine Daunay, Christian Daviaud, Ilef Hchaichi, Caroline Horgues, Mourad Sahbatou, Hélène Le Buanec, Jean‐François Deleuze, Alexandre How‐Kit   +10 more
wiley   +1 more source

Single cell analysis and bioinformatics reveal pyroptosis mechanisms in hepatocellular carcinoma. [PDF]

Discov Oncol
Luo W, JunxiaWang, Wang H, Liu F, Yang T, Wu Z, Guo W.   +6 more
europepmc   +1 more source

RETRACTION: Long Non‐Coding RNA Sox2OT Promotes Coronary Microembolization‐Induced Myocardial Injury by Mediating Pyroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1527-1527, April 2025.
wiley   +1 more source

Pharmacological evaluation of non‐nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury

British Journal of Pharmacology, EarlyView.
Background and purpose Traumatic brain injury (TBI) is considered to be a leading cause of mortality and disability worldwide. After TBI, innate immunity is rapidly activated in response to damage‐associated molecular patterns, such as ATP release, recognised by P2X7 receptors.
Inés Valencia, Andrea Pastor‐Martínez, Céline Decouty‐Pérez, Ana Belen Lopez‐Rodriguez, María Álvarez‐Rubal, Eva Ramos, Francesco Calzaferri, Jorge Zamorano‐Fernández, Javier Giner‐García, Alexis J. Palpán‐Flores, Víctor Rodríguez‐Domínguez, Javier Rodríguez de Cía, Borja J. Hernández‐García, Alejandro Romero, Cristóbal de los Ríos, Javier Egea   +15 more
wiley   +1 more source

CircERC1 facilitates chemoresistance through inhibiting pyroptosis and remodeling extracellular matrix in pancreatic cancer. [PDF]

Mol Cancer
Zhang J, Lv S, Peng X, Liu H, Guo J, Liu Z, Chu T, Liu H, Duan K, Lou F, Chi Y, Gao B, Liu Y, Wei F.   +13 more
europepmc   +1 more source