Results 121 to 130 of about 17,074 (296)

Rhodium-Catalyzed Conversion of Furans to Highly Functionalized Pyrroles

, 2016
The synthesis of highly functionalized pyrroles has been achieved by reaction of rhodium-stabilized imino-carbenes with furans. The reaction features an initial [3+2] annulation to form bicyclic hemiaminals, followed by ring opening to generate ...
Samantha A. Green (1977208), Brendan T. Parr (1651969), Huw M. L. Davies (1336170)   +2 more
core   +1 more source

Synthesis of N-(o-amino aryl) pyrroles by Paal-Knorr reaction [PDF]

, 1971
N-(o-nitro aryl)- and N-(o-acetamino aryl)-2, 5-dimethyl pyrroles are synthesized by Paal-Knorr reaction by condensing acetonyl acetone with o-nitro anilines and o-acetamino anilines respectively.
Subba Rao, N. V., Sudarsana Rao, K., Ratnam, C. V.   +2 more
core   +1 more source

Gold(I)-Catalyzed Intra- and Intermolecular Alkenylations of beta-Yne-pyrroles: Facile Formation of Fused Cycloheptapyrroles and Functionalized Pyrroles

, 2014
An efficient gold(I)-catalyzed alkenylation of beta-alkyne-substituted pyrroles is reported. The intramolecular reaction gives straightforward access to different types of seven-membered-ring-fused pyrroles with endo-selectivity, and the intermolecular ...
Wu, Fan, Wan, Boshun, Hu, Yancheng, Lu, Xiaodong, Pan, Bin, Wang, Chunxiang   +5 more
core   +1 more source

Electrophilic Substitutions of Indoles and Pyrroles:

, 2007
The kinetics of the electrophilic substitutions of indoles and pyrroles have been investigated and new sythetic applications (i.e. electrophilic allylations and benzylations of indoles and regio- and stereoselective ring opening reactions of epoxides ...
Westermaier, Martin
core  

Controlled Oxidation of Pyrroles: Synthesis of Highly Functionalized γ‑Lactams

, 2016
The oxidation of pyrroles usually leads to uncontrolled polymerization and decomposition. To overcome this problem, the controlled oxidation of substituted pyrroles with Dess-Martin periodinane is reported.
James K. Howard (1973647), Jeremy Just (1441951), Jason A. Smith (1441954), Christopher J. T. Hyland (1668883)   +3 more
core   +1 more source

Substituent effect on the electronic and optical properties of newly designed pyrrole derivatives using density functional theory

Open Physics
This work explores six newly designed compounds obtained by several substitutions in 2,5-di(2-thienyl) pyrrole molecule. For this series of compounds, the electronic and optical properties were investigated using density functional theory and time ...
Aljaafreh Mamduh J., Hussein Rageh. K.
doaj   +1 more source

Preparation and functionalization of regioselectively substituted pyrroles/

, 1993
The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles.
Smith, Lana L.
core  

Lewis acid-catalyzed synthesis of functionalized pyrroles

, 2009
The synthesis of highly functionalized pyrroles is described. The sequence involves the preliminary preparation of alpha-aminohydrazones by Michael addition of primary amines to 1,2-diaza-1,3-butadienes.
GIORGI G, BERRETTA, STEFANO, Attanasi, Orazio A., Giorgi, Gianluca, FAVI, GIANFRANCO, ATTANASI, ORAZIO ANTONIO, Lucia De Crescentini, Fabio Mantellini, Orazio A. Attanasi, Stefano Berretta, DE CRESCENTINI, LUCIA, MANTELLINI, FABIO, Gianfranco Favi, Gianluca Giorgi   +13 more
core   +1 more source

Axitinib, cabozantinib, everolimus, nivolumab, sunitinib and best supportive care in previously treated renal cell carcinoma: a systematic review and economic evaluation

Health Technology Assessment, 2018
Background: Several therapies have recently been approved for use in the NHS for pretreated advanced or metastatic renal cell carcinoma (amRCC), but there is a lack of comparative evidence to guide decisions between them.
Steve J Edwards, Victoria Wakefield, Peter Cain, Charlotta Karner, Kayleigh Kew, Mariana Bacelar, Natalie Masento, Fatima Salih   +7 more
doaj   +1 more source

Catalytic Asymmetric Hydrogenation of 2,3,5-Trisubstituted Pyrroles

, 2016
Catalytic asymmetric hydrogenation of N-Boc-protected pyrroles proceeded with high enantioselectivity by using a ruthenium catalyst modified with a trans-chelating chiral bisphosphine PhTRAP.
Masato Ohsumi (2458024), Manabu Kashiwabara (2458027), Hiroki Kusano (2439109), Ryoichi Kuwano (2130856)   +3 more
core   +1 more source