Results 131 to 140 of about 17,074 (296)

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Efficient Synthesis of Highly Functionalised 5-oxo-4,5-Dihydro-1H-Pyrroles and 5-Oxo-2,5-Dihydro-1H-Pyrroles Derivatives

, 2010
Methyl 2-(2-benzoylphenylamino)-2-oxoacetate and dimethyl 2,2′-(4,4′-methylenebis(4,1- phenylene)bis(azanediyl)) bis(2-oxoacetate) undergo a smooth reaction with triphenylphosphine and dialkyl acetylenedicarboxylates to produce corresponding highly ...
Ali Reza Dadrass, Zahra Ranjdost, Ali Souldozi   +2 more
core   +1 more source

New synthetic strategies towards indolizines and pyrroles

, 2015
Indolizines and pyrroles are considered as “privileged” structures since their skeletons were found in many biologically active natural products and they possess a wide range of pharmaceutical properties.
Kücükdisli, Murat
core   +2 more sources

Gold(I)-Catalyzed Intra- and Intermolecular Alkenylations of β‑Yne-pyrroles: Facile Formation of Fused Cycloheptapyrroles and Functionalized Pyrroles

, 2016
An efficient gold­(I)-catalyzed alkenylation of β-alkyne-substituted pyrroles is reported. The intramolecular reaction gives straightforward access to different types of seven-membered-ring-fused pyrroles with endo-selectivity, and the intermolecular ...
Bin Pan (742525), Chunxiang Wang (1748512), Xiaodong Lu (1339779), Yancheng Hu (1819651), Fan Wu (43375), Boshun Wan (1546000)   +5 more
core   +1 more source

Regioselective modification of pyrroles : applications towards lamellarins & pyrrolidine analogues

, 2010
In the past few decades, an extensive family of structurally intriguing and biologically active pyrrolic natural products were recognised. Many of these compounds were isolated from marine organisms and show potent biological activity, and as such have ...
Ng, SMY (15928025)
core   +1 more source

Regioselective Synthesis of 3-Substituted Pyrroles by Nucleophilic Addition of 3-(1-Arylsulfonylalkyl) Pyrroles Activated under Basic or Acid Conditions

, 2011
Sulfonyl pyrroles, obtained regioselectively from commercial N-triisopropylsilylpyrrole, undergo removal of the arylsulfonyl group under basic or acidic conditions to give vinylogous imino-like derivatives (see scheme; TIPS=triisopropylsilyl).
MARTINELLI, FABIO, Fabio Martinelli, Alessandro Palmieri, PETRINI, Marino, Marino Petrini, PALMIERI, Alessandro   +5 more
core   +1 more source

Facile Synthesis of N-Aryl Pyrroles via Cu(II)-Mediated Cross Coupling of Electron Deficient Pyrroles and Arylboronic Acids

, 2016
N-Arylation of electron-deficient pyrroles has been achieved by cross-coupling with arylboronic acids at room temperature in the presence of stoichiometric amounts of copper(II) acetate. The generality of this reaction has been established with variously
Jayaram K. Srirangam (2998734), James Saenz (1656892), Shu Yu (645086)   +2 more
core   +1 more source

Construction of Lean Coal Molecular Structure Model Based on Spectroscopic Characterization

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The chemical structure of coal exerts a profound influence on its properties and utilization pathways. A comprehensive analysis of coal's molecular structure is crucial for mitigating environmental pollution arising from coal combustion and improving the efficiency of coal utilization.
Song Liu, Hao Xia, Tao Ge, Yaling Bai, Shoulan Wang, Yunfang Liu   +5 more
wiley   +1 more source

Rhodium-Catalyzed Transannulation of 1,2,3-Triazoles to Polysubstituted Pyrroles

, 2016
Rhodium-catalyzed transannulation of N-sulfonyl-1,2,3-triazoles with vinyl ether has been accomplished for the synthesis of various polysubstituted pyrroles.
Pazhamalai Anbarasan (1555108), Shanmugam Rajasekar (1754086)   +1 more
core   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source