Electrophilic Substitutions of Indoles and Pyrroles: [PDF]
, 2007 The kinetics of the electrophilic substitutions of indoles and pyrroles have been investigated and new sythetic applications (i.e. electrophilic allylations and benzylations of indoles and regio- and stereoselective ring opening reactions of epoxides ...
Westermaier, Martin
core
Controlled Oxidation of Pyrroles: Synthesis of Highly Functionalized γ‑Lactams [PDF]
, 2016 The oxidation of pyrroles usually leads to uncontrolled polymerization and decomposition. To overcome this problem, the controlled oxidation of substituted pyrroles with Dess-Martin periodinane is reported.
James K. Howard (1973647) +3 more
core +1 more source
Preparation and functionalization of regioselectively substituted pyrroles/ [PDF]
, 1993 The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles.
Smith, Lana L.
core
Lewis acid-catalyzed synthesis of functionalized pyrroles [PDF]
, 2009 The synthesis of highly functionalized pyrroles is described. The sequence involves the preliminary preparation of alpha-aminohydrazones by Michael addition of primary amines to 1,2-diaza-1,3-butadienes.
GIORGI G +13 more
core +1 more source
The intricacies of the stacking interaction in a pyrrole–pyrrole system [PDF]
Structural Chemistry, 2016 Extensive calculations of potential energy surfaces for parallel-displaced configurations of pyrrole–pyrrole systems have been carried out by the use of a dispersion-corrected density functional. System geometries associated with the energy minima have been found. The minimum interaction energy has been calculated as −5.38 kcal/mol.
openaire +1 more source
Catalytic Asymmetric Hydrogenation of 2,3,5-Trisubstituted Pyrroles [PDF]
, 2016 Catalytic asymmetric hydrogenation of N-Boc-protected pyrroles proceeded with high enantioselectivity by using a ruthenium catalyst modified with a trans-chelating chiral bisphosphine PhTRAP.
Masato Ohsumi (2458024) +3 more
core +1 more source
Efficient Synthesis of Highly Functionalised 5-oxo-4,5-Dihydro-1H-Pyrroles and 5-Oxo-2,5-Dihydro-1H-Pyrroles Derivatives [PDF]
, 2010 Methyl 2-(2-benzoylphenylamino)-2-oxoacetate and dimethyl 2,2′-(4,4′-methylenebis(4,1- phenylene)bis(azanediyl)) bis(2-oxoacetate) undergo a smooth reaction with triphenylphosphine and dialkyl acetylenedicarboxylates to produce corresponding highly ...
Ali Reza Dadrass +2 more
core +1 more source
New synthetic strategies towards indolizines and pyrroles [PDF]
, 2015 Indolizines and pyrroles are considered as “privileged” structures since their skeletons were found in many biologically active natural products and they possess a wide range of pharmaceutical properties.
Kücükdisli, Murat
core +4 more sources
Gold(I)-Catalyzed Intra- and Intermolecular Alkenylations of β‑Yne-pyrroles: Facile Formation of Fused Cycloheptapyrroles and Functionalized Pyrroles [PDF]
, 2016 An efficient gold(I)-catalyzed alkenylation of β-alkyne-substituted pyrroles is reported. The intramolecular reaction gives straightforward access to different types of seven-membered-ring-fused pyrroles with endo-selectivity, and the intermolecular ...
Bin Pan (742525) +5 more
core +1 more source
Regioselective modification of pyrroles : applications towards lamellarins & pyrrolidine analogues [PDF]
, 2010 In the past few decades, an extensive family of structurally intriguing and biologically active pyrrolic natural products were recognised. Many of these compounds were isolated from marine organisms and show potent biological activity, and as such have ...
Ng, SMY (15928025)
core +1 more source