Results 81 to 90 of about 26,582 (202)

Analysis of the flavonoid component of bioactive New Zealand mānuka (Leptospermum scoparium) honey and the isolation, characterisation and synthesis of an unusual pyrrole [PDF]

open access: yes, 2013
The flavonoid components of New Zealand mānuka (Leptospermum scoparium) honey have been quantified in a series of 31 honeys of varying non-peroxide antibacterial activity to clarify discrepancies between previous studies reported in the literature. Total
Alber, Dagmar G.   +5 more
core   +2 more sources

Synthesis and in vitro study of redox properties of pyrrole and halogenated pyrrole derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society
The redox balance plays a crucial role in maintaining biological processes under normal conditions. Antioxidants inhibit and reduce harmful oxidation processes, while pro-oxidants can act as anti-cancer agents by promoting ROS-mediated cell death.
Petković Miloš R.   +7 more
doaj   +1 more source

N-Heterocyclic carbene–palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides

open access: yesBeilstein Journal of Organic Chemistry, 2013
New Pd–NHC complexes have been synthesized and employed for palladium-catalyzed direct arylation of pyrrole derivatives by using electron-deficient aryl chlorides as coupling partners.
Ismail Özdemir   +6 more
doaj   +1 more source

Application of Flow Thermolysis in Organic Synthesis: Easy Access to α,ω-Bis Thienyl- and Bis Pyrrolyl- Alkanes from Methylene Derivatives of Meldrum's Acid

open access: yesMolecules, 2000
Thermal decomposition of Meldrum's acid derivatives and rearrangement of (alkylsulfanyl) or (propargylamino)methylene ketene intermediates leads in one step to bis thienyl- or bis pyrrolyl-alkanes.
Hamid Dhimane   +2 more
doaj   +1 more source

Synthetic utility and reactivity of N-alkynylazoles [PDF]

open access: yes, 2015
textThe chemistry of N-alkynylazoles is a newly emerging area of chemistry with particular interest in heterocycle synthesis. Synthetic preparations of this class of molecule have shown an increasing presence in literature, however, the synthetic ...
Gilbreath, Bradford Lynd
core  

A theoretical study of the mechanism of rearrangement of dihydropyrimidines into pyrroles [PDF]

open access: yes, 2017
Pyrimidines, pyrroles, cycloreversion,CO extrusion, Two possible mechanisms for the transformation of a 1,4-dihydropyrrolo[3,2-b]pyrrole derivative into a tetrasubstituted pyrrole have been studied theoretically and one of them has been found in ...
Alkorta, I., de la Hoz, A., Elguero, J.
core  

Substituent effect on the electronic and optical properties of newly designed pyrrole derivatives using density functional theory

open access: yesOpen Physics
This work explores six newly designed compounds obtained by several substitutions in 2,5-di(2-thienyl) pyrrole molecule. For this series of compounds, the electronic and optical properties were investigated using density functional theory and time ...
Aljaafreh Mamduh J., Hussein Rageh. K.
doaj   +1 more source

Axitinib, cabozantinib, everolimus, nivolumab, sunitinib and best supportive care in previously treated renal cell carcinoma: a systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2018
Background: Several therapies have recently been approved for use in the NHS for pretreated advanced or metastatic renal cell carcinoma (amRCC), but there is a lack of comparative evidence to guide decisions between them.
Steve J Edwards   +7 more
doaj   +1 more source

A General Diastereoselective Catalytic Vinylogous Aldol Reaction Among Tetramic Acid-Derived Pyrroles [PDF]

open access: yes, 2015
A catalytic diastereoselective aldol reaction has been developed for N1-arylated/C2-O-silylated/C3-methylated and brominated/C4-O-methylated pyrroles in its reactions with various aldehydes.
David, Jonathan Gene
core   +1 more source

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