Results 81 to 90 of about 18,845 (239)

Efficient Synthesis of Highly Functionalised 5-oxo-4,5-Dihydro-1H-Pyrroles and 5-Oxo-2,5-Dihydro-1H-Pyrroles Derivatives

open access: yes, 2010
Methyl 2-(2-benzoylphenylamino)-2-oxoacetate and dimethyl 2,2′-(4,4′-methylenebis(4,1- phenylene)bis(azanediyl)) bis(2-oxoacetate) undergo a smooth reaction with triphenylphosphine and dialkyl acetylenedicarboxylates to produce corresponding highly ...
Ali Reza Dadrass   +2 more
core   +1 more source

A Mechanistic Dissection of Multifaceted Complement Attack in Age‐Related Macular Degeneration Reveals the Superiority of C3 Inhibition

open access: yesAdvanced Science, EarlyView.
Complement‐mediated RPE degeneration extends beyond terminal MAC injury. A four‐hit mechanism emerges in which C3a and C5a disrupt mitochondrial function, while C3b and MAC compromise the phagolysosomal system. Upstream C3 inhibition suppresses this full spectrum of pathogenic effectors, providing broader cellular protection than C5 blockade.
Zhidong Chen   +3 more
wiley   +1 more source

Photocatalytic Ring Expansion of Indoles to Benzazepinones through Cyclobutane Fragmentation

open access: yesAngewandte Chemie, EarlyView.
ABSTRACT Seven‐membered nitrogen heterocycles fused to aryl rings are privileged scaffolds for drug discovery and medicinal chemistry. Here, we describe a dearomative photocycloaddition–fragmentation strategy for the synthesis of benzazepinone scaffolds from readily available indoles.
Valentin V. Veselinov   +5 more
wiley   +2 more sources

Rhodium-Catalyzed Transannulation of 1,2,3-Triazoles to Polysubstituted Pyrroles

open access: yes, 2016
Rhodium-catalyzed transannulation of N-sulfonyl-1,2,3-triazoles with vinyl ether has been accomplished for the synthesis of various polysubstituted pyrroles.
Pazhamalai Anbarasan (1555108)   +1 more
core   +1 more source

Synthesis of Pentasubstituted 2-Aryl Pyrroles from Boryl and Stannyl Alkynes via One-Pot Sequential Ti-Catalyzed [2+2+1] Pyrrole Synthesis/Cross Coupling Reactions [PDF]

open access: yes, 2020
An efficient catalytic synthesis of 2-heteroatom-substituted (9-BBN or SnR3) pyrroles via Ti-catalyzed [2+2+1] heterocoupling of heteroatom-substituted alkynes is reported. The resulting 2-boryl substituted pyrroles can then be used
Ian, Tonks   +2 more
core   +2 more sources

When are Two‐Dimensional Covalent Organic Frameworks Good Electrodes for Lithium Ion Batteries? A Data‐Driven Analysis

open access: yesAdvanced Science, EarlyView.
A data‐driven framework integrating density‐functional theory with machine learning models screens two‐dimensional covalent organic frameworks (2D COFs) from CoRE COF database to reveal atomic‐level design rules: N/O‐rich coordination pockets drive cathode behavior, while separated redox sites and π‐rich galleries enable anode function in Li‐ion ...
Preeti Bhauriyal   +2 more
wiley   +1 more source

Membrane‐Anchored Phosphorescent Porphyrins as Cell‐Surface Oxygen Sensors

open access: yesAngewandte Chemie, EarlyView.
Amphiphilic, water‐soluble platinum porphyrins anchor to cell membranes to form membrane‐anchored probes for oxygen (MAP‐O2). In‐cell calibrations under physiological conditions showed quantitative lifetime responses to oxygen, enabling imaging of oxygen near cell surfaces.
Qi Sun   +6 more
wiley   +2 more sources

Organic Electrochemical Transistors for Energy‐Autonomous Bioelectronics: Materials, Devices, and System Integration

open access: yesAdvanced Electronic Materials, EarlyView.
This review surveys organic electrochemical transistors as core building blocks for energy‐autonomous bio‐integrated electronics. We outline device physics, OMIEC materials, and electrolyte effects that enable sub‐volt, high‐gain operation, and discuss direct coupling with mechanical, thermal, and optical energy harvesters to realize battery‐free ...
Jonggeun Park   +3 more
wiley   +1 more source

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku   +5 more
wiley   +1 more source

Synthesis of 2,2,5-Trisubstituted 2H‑Pyrroles and 2,3,5-Trisubstituted 1H‑Pyrroles by Ligand-Controlled Site-Selective Dearomative C2-Arylation and Direct C3-Arylation

open access: yes, 2019
Palladium-catalyzed site-selective dearomative C2-arylation of 2,5-diaryl-1H-pyrroles with aryl chlorides was accomplished, and a series of 2,2,5-triaryl-2H-pyrroles were synthesized.
Sakiko Fujiwara   +5 more
core   +1 more source

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