Results 201 to 210 of about 70,546 (390)

Clinical Evaluation of Potential Interaction Between Bemnifosbuvir and Ruzasvir With an Assessment of Food Effect: Results of a Phase 1 Study in Healthy Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A combination of nucleotide hepatitis C virus (HCV) nonstructural protein (NS) 5B and 5A inhibitors is a preferred standard of care for treating chronic HCV. Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against HCV NS5B.
Xiao‐Jian Zhou   +7 more
wiley   +1 more source

Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Xiaoqing Zheng   +10 more
semanticscholar   +1 more source

Harnessing Fluorine Chemistry: Strategies for Per‐ and Polyfluoroalkyl Substances Removal and Enrichment

open access: yesChemPlusChem, EarlyView.
The high fluorine content in per‐ and polyfluoroalkyl substances (PFAS) gives them unique properties, leading to their widespread use in industrial applications and consumer products, but also creating environmental challenges . A thorough understanding of PFAS fluorine chemistry is crucial for developing effective concentration technologies ...
Anne Lobitz   +3 more
wiley   +1 more source

En Route Toward Sustainable Polycarbonates Via Large Cyclic Carbonates

open access: yesChemSusChem, Accepted Article.
This review reports an up‐to‐date overview of the synthetic methodologies developed for the preparation of large cyclic organic carbonates with ≥ 6‐membered rings (6M‐CCs and above), highlighting the most sustainable synthetic pathways employing diols (including renewable‐based ones) and non‐hazardous carbonyl sources, e.g., linear organic carbonates ...
Francesco Della Monica   +5 more
wiley   +1 more source

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