Results 201 to 210 of about 54,719 (255)

Synthesis of 3-substituted pyrrolidines

Chemistry of Heterocyclic Compounds, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A. V. Kurkin, E. A. Sumtsova, M. A. Yurovskaya   +2 more
openaire   +1 more source

Telescoped Synthesis of Stereodefined Pyrrolidines

Organic Letters, 2013
Telescoped and one-pot olefination/asymmetric functionalization approaches to disubstituted pyrrolidines (dr up to 99:1, up to 99% ee) have been developed using commercially available tetramisole (0.1 to 5 mol %). Using OTMS-quinidine as the Lewis base gives preferential access to an anti-configured pyrrolidine in high enantioselectivity.
Dorine Belmessieri, David B. Cordes, Alexandra M. Z. Slawin, Andrew D. Smith   +3 more
openaire   +2 more sources

Pyrrolidine dithiocarbamate reduced experimental periodontitis

European Journal of Pharmacology, 2006
Nuclear factor-kappaB (NF-kappaB) is a transcription factor which plays a pivotal role in the induction of genes involved in physiological processes as well as in the response to injury and inflammation. Dithiocarbamates are antioxidants which are potent inhibitors of NF-kappaB.
MUIA C, MAZZON E, MAIERE D, ZITO D, DI PAOLA R, DOMENICO S, CRISAFULLI, CONCETTA, BRITTI D, CUZZOCREA, Salvatore, DI PAOLA, ROSANNA   +9 more
openaire   +2 more sources

Synthesis of pyrrolidine-2–14C

Journal of Pharmaceutical Sciences, 1967
The preparation of pyrrolidine-2– 14 C picrate in satisfactory yields from potassium cyanide- 14 C and from barium carbonate- 14 C is reported. Reaction of pyrrolidine picrate with lithium hydroxide followed by distillation separated the free base.
J M, Walts, W V, Kessler, J E, Christian
openaire   +2 more sources

[60]Fullerene−Pyrrolidine-N-oxides

The Journal of Organic Chemistry, 2006
Eight members of a new family of fullerene derivatives, [60]fulleropyrrolidine-N-oxides, have been synthesized and characterized. Facile oxidation, by a peracid, of the parent [60]fulleropyrrolidine gave clean conversions into the product molecules, in which the tertiary amine is transformed into a quaternary amine bearing an oxygen atom.
P. BROUGH, C. KLUMPP, A. BIANCO, S. CAMPIDELLI, PRATO, MAURIZIO   +4 more
openaire   +3 more sources

Syntheses de Pyrrolidines Deuteriees

Journal of Labelled Compounds, 1974
AbstractCinq pyrrolidines di ou tétradeutériées ont été préparées soit par réduction de la cétone correspondante (dideutério‐2,2 pyrrolidine), soit à partir du dérivé N nitrosé après échange en milieu basique (tétradeutério‐2,2,5,5 pyrrolidine) soit enfin par cyclisation d'une chaǐne aliphatique marquée en position souhaitée (dideutério‐3,3 ...
D. Rogic, M. F. Lautie, P. Dizabo, L. C. Leitch   +3 more
openaire   +1 more source

Organophosphorus derivatives of pyrrolidine

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1974
Some 2-oxo-2-pyrrolidino-1,3,2-dioxaphospholanes and the corresponding phosphorinanes, and also some 2-thio-2-pyrrolidino-1,3,2-dioxaphospholanes (phosphorinanes), were obtained for the first time. These compounds have an antispasmodic effect and the ability to depress the central nervous system.
N. P. Grechkin, L. N. Grishina
openaire   +1 more source

Pyrrolidines

2021
Jie Jack Li, Minmin Yang
openaire   +1 more source

Spirocyclic Pyrrolidines

2021
Jie Jack Li, Minmin Yang
openaire   +1 more source

Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

Topics in Current Chemistry, 2021
Giovanna LI PETRI, Maria Valeria Raimondi, Ralph Holl   +2 more
exaly