Results 81 to 90 of about 172,060 (247)

Blood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome

Drug Design, Development and Therapy, 2015
Hong Gao,1,* Jianqing Q Ruan,2,* Jie Chen,1 Na Li,2 Changqiang Q Ke,3 Yang Ye,3–5 Ge Lin,2,4,5 Jiyao Y Wang1,61Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 2School of Biomedical ...
Gao H, Ruan JQ, Chen J, Li N, Ke CQ, Ye Y, Lin G, Wang JY   +7 more
doaj  

Advances in Pharmacological Insights of Borago officinalis: A Comprehensive Review

Biological Diversity, Volume 2, Issue 4, Page 193-205, December 2025.
ABSTRACT Recent growth in phytotherapy and product‐based drug development has increased interest in this plant because of its broad pharmacological activity. This review aims to examine the pharmacological activities, mechanisms, and potential applications of Borago officinalis, focusing on its primary bioactive constituents and therapeutic ...
Zahra Sufwan, Javed Akhtar Ansari, Farogh Ahsan   +2 more
wiley   +1 more source

Radioactive Tracer Feeding Experiments and Product Analysis to Determine the Biosynthetic Capability of Comfrey (Symphytum officinale) Leaves for Pyrrolizidine Alkaloids

Bio-Protocol, 2018
This protocol delivers a method to determine the biosynthetic capability of comfrey leaves for pyrrolizidine alkaloids independently from other organs like roots or flowers.The protocol applies and combines radioactive tracer experiments with standard ...
Thomas Stegemann, Lars Kruse, Dietrich Ober   +2 more
doaj   +1 more source

The concerning food safety issue of pyrrolizidine alkaloids: An overview

Trends in Food Science & Technology, 2022
Natalia Casado, Sonia Morante-Zarcero, I. Sierra   +2 more
semanticscholar   +1 more source

The Monocrotaline Model of Hypertension Leads to Cachexia in Male but Not Female Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background The monocrotaline (MCT) model of cardiac cachexia is a pharmaceutical approach to pulmonary hypertension that has been used to study heart failure and muscle wasting in rodents; however, little is known of how this pyrrolizidine alkaloid leads to peripheral changes in organ function and body mass, and sex differences have not been ...
Abbey L. Politeski, Alexander Q.L Rico, Jack Cambell, Julio G. Cisneros Medrano, Ben Witmer, Risha Gupta, Noah A. Fiorucci, Katherine M. Lycett, Hannah C. Smith, Hannah M. Kavanagh, Cayleih E. Robertson, Ingrid K. M. Brenner, Aaron B. A. Shafer, Holly E. Bates, Kirk Hillsley, Stephanie W. Tobin   +15 more
wiley   +1 more source

Dutch survey pyrrolizidine alkaloids in animal forage [PDF]

Pyrrolizidine alkaloids (PAs) are secondary plant metabolites produced by a number of plants from the Asteraceae (Compositae), Boriginaceae and Fabaceae (Leguminosae) families.
Beumer, B., Jong, J., de, Mulder, P.P.J., Oosterink, J.E.   +3 more
core   +1 more source

Effects of soil nutrients on the sequestration of plant defence chemicals by the specialist insect herbivore, Danaus plexippus [PDF]

, 2015
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110863/1/een12168 ...
Agrawal, Anderson, Awmack, Bernays, Bobbink, Boersma, Bowers, Bowers, Bowers, Brower, Brower, Bukovinszky, Burghardt, Camara, Cohen, Cohen, Dobler, Docherty, Elser, Erickson, Fenn, Fordyce, Frick, Galloway, Hartmann, Hartmann, Holzinger, Jamieson, Kearsley, Keating, Keinänen, Lefevre, Lynch, Malcolm, Malcolm, Mattson, Nishida, Opitz, Prudic, Rasmann, Reichstein, Roode, Sternberg, Tao, Tao, Throop, Vaughan, Vitousek, Vitousek, Zalucki, Zehnder, Zehnder   +51 more
core   +1 more source

Animal medical systems from Apis to apes: history, recent advances and future perspectives

Biological Reviews, Volume 100, Issue 6, Page 2608-2624, December 2025.
ABSTRACTAnimal medical systems encompass a wide range of behaviours aimed at maintaining or improving health. It has become clear that these behaviours are not limited to animals treating themselves (self‐medication) but also include the treatment of group members, resulting in the adoption of the more inclusive term “animal medication”. Behaviour with
Michelina Pusceddu, Michael A. Huffman, Stephane Knoll, Ana Helena Dias Francesconi, Ignazio Floris, Alberto Satta   +5 more
wiley   +1 more source

Uji Efikasi Ekstrak Gulma Siam Terhadap Mortalitas Hama Pencucuk Buah Kakao (Helopeltis Spp.) Di Laboratorium [PDF]

, 2012
This research was aimed to investigate the effect of siam weeds (C. odorata) extract on the mortality of Helopeltis spp., the effect of the addition of emulsifier on the toxicity of siam weed extract, and to find out a potential concentration of the ...
Fitriana, Y. (Yuyun), Hariri, A. M. (Agus), Purnomo, P. (Purnomo)   +2 more
core  

Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models

Molecular Medicine Reports, 2018
Pyrrolizidine alkaloids (PAs) are a widespread class of hepatotoxic heterocyclic organic compounds found in approximately 3% of world flora. Some PAs have been shown to have genotoxic and carcinogenic effects.
O. Șeremet, O. T. Olaru, C. Guțu, G. Nițulescu, M. Ilie, S. Negreș, C. E. Zbârcea, C. Purdel, D. Spandidos, A. Tsatsakis, M. Coleman, D. Margină   +11 more
semanticscholar   +1 more source