Results 121 to 130 of about 5,329 (163)

Nutritional Importance of Pyrroloquinoline Quinone

Science, 1989
Mice fed a chemically defined diet devoid of pyrroloquinoline quinone (PQQ) grew poorly, failed to reproduce, and became osteolathyritic. Moreover, severely affected mice had friable skin, skin collagen that was readily extractable into neutral salt solutions, and decreased lysyl oxidase.
J, Killgore, C, Smidt, L, Duich, N, Romero-Chapman, D, Tinker, K, Reiser, M, Melko, D, Hyde, R B, Rucker   +8 more
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Detection of the cofactor pyrroloquinoline quinone

Analytical Biochemistry, 1987
In order to demonstrate the presence or absence of a pyrroloquinoline quinone (PQQ) synthesizing capacity in microorganisms, we have found that media and equipment must be treated to remove contaminating PQQ. Procedures are described which appear to be effective for that purpose.
M A, van Kleef, P, Dokter, A C, Mulder, J A, Duine   +3 more
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Pyrroloquinoline Quinone: A Novel Cofactor

1989
Publisher Summary This chapter discusses the properties, distribution, and biosynthesis of pyrroloquinoline quinine (PQQ). PQQ is an essential cofactor for several key enzymes in physiological processes in mammals. Development of inhibitors specifically directed to PQQ might reveal the role of PQQ and quinoproteins, but also that of vitamin B, and ...
J A, Duine, J A, Jongejan
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A Periplasmic Binding Protein for Pyrroloquinoline Quinone

Biochemistry, 2019
Pyrroloquinoline quinone (PQQ) is an essential redox cofactor in bacterial calcium- and lanthanide-dependent alcohol dehydrogenases. Although certain bacteria are known to synthesize and secrete PQQ, little is known about trafficking of this cofactor within and between cells.
Jackson V. Ho, Joseph A. Cotruvo
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Biochemical and Physiological Functions of Pyrroloquinoline Quinone

1991
Publisher Summary This chapter discusses the biochemical and physiological functions of pyrroloquinoline quinone (PQQ). Quinoproteins are distributed widely among prokaryotic and eukaryotic organisms. The prosthetic group of copper-containing amine oxidases from mammals, plants, and microorganisms have been identified as PQQ bound covalently to the ...
M, Ameyama, K, Matsushita, E, Shinagawa, O, Adachi   +3 more
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Nephrotoxicity of pyrroloquinoline quinone in rats.

Hiroshima journal of medical sciences, 1989
When pyrroloquinoline quinone (PQQ) was intraperitoneally injected into rats daily for 4 days at a dose of 11.5 mg/kg body weight/injection, functional and morphologic changes of the kidneys were clearly observed. The most prominent finding was necrotic and degenerative changes of the proximal tubular epithelium as well as hematuria and an elevation of
Watanabe, Akiharu, Hobara, Norio, Ohsawa, Toshiya, Higashi, Toshihiro, Tsuji, Takao   +4 more
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Pyrroloquinoline Quinone (PQQ) and Quinoprotein Enzymes

Antioxidants & Redox Signaling, 2001
This review summarises the characteristics, identification, and measurement of pyrroloquinoline quinone, the prosthetic group of bacterial quinoprotein dehydrogenases whose structures, mechanisms, and electron transport functions are described in detail. Type I alcohol dehydrogenase includes the "classic" methanol dehydrogenase; its x-ray structure and
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Nutritional Essentiality of Pyrroloquinoline Quinone

1989
A chemically defined diet, based on synthetic amino acids, was fed to rats and mice. The control diet (+PQQ) was fortified with pyrroloquinoline quinone (PQQ) at 875 ug/kg. The deficient diet (-PQQ) contained no detectable PQQ. The -PQQ diet was fed to pregnant rats and, in later experiments, to mice throughout gestation. Newborn pups remained with the
Robert Rucker, John Killgore, Lisa Duich, Nadia Romero-Chapman, Carsten Smidt, Donald Tinker   +5 more
openaire   +1 more source

Determination of pyrroloquinoline quinone by capillary zone electrophoresis

Journal of Chromatography B: Biomedical Sciences and Applications, 2000
A new method for the determination of pyrroloquinoline quinone by capillary zone electrophoresis has been developed. Separation conditions have been optimised with the respect to different parameters including pH and ionic strength of the background electrolyte, separation voltage and temperature of the capillary.
Z, Glatz, M, Moravcová, O, Janiczek
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Detection and determination of pyrroloquinoline quinone, the coenzyme of quinoproteins

Analytical Biochemistry, 1983
A convenient determination of pyrroloquinoline quinone (PQQ) in extracts of purified enzymes is possible with ion-pair chromatography on a HPLC reverse-phase column and with uv detection. However, when culture supernatants have to be analyzed, a fluorescence detection system is more appropriate. Proof for the presence of PQQ can be obtained by treating
J A, Duine, J, Frank, J A, Jongejan
openaire   +2 more sources