Results 181 to 190 of about 4,988 (210)
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Pyrroloquinoline Quinone (PQQ) and Quinoprotein Enzymes
Antioxidants & Redox Signaling, 2001This review summarises the characteristics, identification, and measurement of pyrroloquinoline quinone, the prosthetic group of bacterial quinoprotein dehydrogenases whose structures, mechanisms, and electron transport functions are described in detail. Type I alcohol dehydrogenase includes the "classic" methanol dehydrogenase; its x-ray structure and
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Acid-promoted tautomeric lactonization and oxidation-reduction of pyrroloquinoline quinone (PQQ)
Biochemical and Biophysical Research Communications, 1989Acid-treatment facilitates PQQ detection by electron ionization mass spectroscopy with a molecular ion at M/e 330 and a base ion formed by triple decarboxylation at M/e 198. Other ions found probably arise through acid-catalyzed tautomeric lactonization of PQQ to PQQ-lactone (PQQL) with subsequent oxidation of PQQL and reduction of PQQ. We propose that
P M, Gallop +4 more
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Journal of the American College of Nutrition, 2019
Objective: Pyrroloquinoline quinone (PQQ) is a novel supplement involved in processes such as mitochondrial biogenesis and cellular energy metabolism.
Paul S. Hwang +6 more
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Objective: Pyrroloquinoline quinone (PQQ) is a novel supplement involved in processes such as mitochondrial biogenesis and cellular energy metabolism.
Paul S. Hwang +6 more
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Life Sciences, 1993
The effects of pyrroloquinoline quinone (PQQ) and PQQ-oxazole (PQQ-glycine adduct) on DNA synthesis were examined using cultured human fibroblasts. Confluent fibroblasts were cultured in serum-free Dulbecco's modified Eagle's media, and various concentrations of PQQ and PQQ-oxazole were added to the media.
Y, Naito +3 more
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The effects of pyrroloquinoline quinone (PQQ) and PQQ-oxazole (PQQ-glycine adduct) on DNA synthesis were examined using cultured human fibroblasts. Confluent fibroblasts were cultured in serum-free Dulbecco's modified Eagle's media, and various concentrations of PQQ and PQQ-oxazole were added to the media.
Y, Naito +3 more
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The Pyrroloquinoline Quinone (PQQ) Coenzymes: A Case of Mistaken Identity
Nutrition Reviews, 2009Recent evidence has failed to support the claim for a pyrroloquinoline quinone (PQQ) cofactor in mammalian enzymes previously reported to have PQQ. The validity of the original analysis now has been questioned, and a second cofactor, topa quinone, has been identified in at least one enzyme.
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Synthesis of Imidazolo Analogues of the Oxidation−Reduction Cofactor Pyrroloquinoline Quinone (PQQ)
The Journal of Organic Chemistry, 2004Parallel syntheses of 2-hydro-, 2-methyl-, and 2-methoxycarbonylimidazo-7,9-dimethoxycarbonyl analogues of the oxidation-reduction cofactor pyrroloquinoline quinone [4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid] have been developed. The properties of the imidazolo analogues in relation to the corresponding pyrrole analogues
David M D, Fouchard +2 more
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A subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt in rats.
Food and Chemical Toxicology, 2015A subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt was performed in rats. Sprague-Dawley rats were randomly divided into four groups (10 rats/sex/group) and administered with PQQ disodium salt at doses of 0 (control), 100, 200 and 400 mg/kg bw/day by gavage for 13 weeks.
Chunlai Liang +4 more
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ChemInform Abstract: Synthesis of Isomeric Analogues of Coenzyme Pyrroloquinoline Quinone ( PQQ).
ChemInform, 1996AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Z. ZHANG +2 more
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Effect of pyrroloquinoline quinone (PQQ) on melanogenic protein expression in murine B16 melanoma
Journal of Dermatological Science, 2009Increased production and accumulation of melanin leads to various hyperpigmentation disorders. Melanin synthesis is regulated by melanogenic proteins such as tyrosinase, tyrosinase-related protein (TRP)-1 and -2, and their transcription factors.In this study, we assessed the effects of PQQ on melanogenic protein expression of murine B16 melanoma cells ...
Kazuomi, Sato, Masaru, Toriyama
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2000
Radiochemical forms of pyrroloquinoline quinone (PQQ) are of utility in studies to determine the metabolic role and fate of PQQ in biological systems. Accordingly, we have synthesized [(14)C]PQQ using a tyrosine auxotrophic strain of Escherichia coli (AT2471).
T E, Stites, T R, Sih, R B, Rucker
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Radiochemical forms of pyrroloquinoline quinone (PQQ) are of utility in studies to determine the metabolic role and fate of PQQ in biological systems. Accordingly, we have synthesized [(14)C]PQQ using a tyrosine auxotrophic strain of Escherichia coli (AT2471).
T E, Stites, T R, Sih, R B, Rucker
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