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Synthesis of Imidazolo Analogues of the Oxidation−Reduction Cofactor Pyrroloquinoline Quinone (PQQ)

The Journal of Organic Chemistry, 2004
Parallel syntheses of 2-hydro-, 2-methyl-, and 2-methoxycarbonylimidazo-7,9-dimethoxycarbonyl analogues of the oxidation-reduction cofactor pyrroloquinoline quinone [4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid] have been developed. The properties of the imidazolo analogues in relation to the corresponding pyrrole analogues
David M D, Fouchard   +2 more
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Effects of pyrroloquinoline quinone (PQQ) on skin wound healing in mice

Surgery
Wound healing is a dynamic process that begins following the destruction of the skin's normal anatomy. This study evaluated effects of pyrroloquinoline quinone on skin wounds in mice.Thirty-six male mice were randomly divided in to 3 groups: (1) Sham group, where wounds were created but no treatment was administered; (2) Soybean oil, where soybean oil ...
Farshid Davoodi   +5 more
openaire   +2 more sources

Pyrroloquinoline quinone (PQQ): Role in Plant-Microbe Interactions

2019
Pyrroloquinoline quinone (PQQ) is synthesized by only some bacteria, but it has an impact on many organisms, including plant growth-promoting bacteria. This molecule can modify some microbial process such as gene expression, metabolism, among others, which have potential advantageous effects on plants.
R. Carreño-López   +2 more
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Current study on Pyrroloquinoline quinone (PQQ) therapeutic role in neurodegenerative diseases

Molecular Biology Reports
Pyrroloquinoline quinone (PQQ) is a naturally occurring redox-active compound with potent antioxidant, mitochondrial-enhancing, and neuroprotective properties. Originally identified as a cofactor in bacterial enzymes, PQQ has garnered significant interest for its potential therapeutic role in neurodegenerative diseases, including Alzheimer's disease ...
Lingbo Kong, Mingzhe Feng
exaly   +3 more sources

A subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt in rats

Food and Chemical Toxicology, 2015
A subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt was performed in rats. Sprague-Dawley rats were randomly divided into four groups (10 rats/sex/group) and administered with PQQ disodium salt at doses of 0 (control), 100, 200 and 400 mg/kg bw/day by gavage for 13 weeks.
Chunlai, Liang   +4 more
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ChemInform Abstract: Novel Function of the Pyrroloquinoline Quinone, PQQ, Enhanced by Micelle.

Chemischer Informationsdienst, 1984
AbstractPyrrolochinolinchinon (PQQ) (I), das als Coenzym einiger Dehydrogenasen isoliert worden ist, katalysiert die Luft‐Oxidation von Cyclohexylamin zu Cyclohexanon.
Y. OHSHIRO, T. HIRAO, T. AGAWA
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Pyrroloquinoline quinone (PQQ) biosynthesis

Acta Crystallographica Section A Foundations of Crystallography, 2007
S. Puehringer, R. Schwarzenbacher
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Pyrroloquinoline quinone (coenzyme PQQ) and the oxidation of SH residues in proteins.

BioFactors (Oxford, England), 1992
Pyrroloquinoline quinone (PQQ) catalyzes the oxidation of cysteamine at neutral pH with a second order rate constant K2 = 0.45 M-1 s-1. The reduction of PQQ was monitored by absorption and fluorescence spectroscopy, whereas the oxidation of cysteamine to cystamine was followed by titration with 5,5'-dithiobis(2-nitrobenzoic acid).
J, Park, J E, Churchich
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Crystal Structure of a Ytterbium(III)–Pyrroloquinoline Quinone (PQQ) Complex

Pyrroloquinoline quinone (PQQ) is a redox-active quinone-based cofactor best known for its role in bacterial alcohol dehydrogenases, including a subset of lanthanide-dependent enzymes discovered in recent years. To gain further structural insight into lanthanide-PQQ coordination chemistry, we report the crystal structure of [YbPQQ(H
Jonathan Gutenthaler-Tietze   +2 more
openaire   +1 more source

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