Results 61 to 70 of about 4,988 (210)

Role of glutathione in augmenting the anticancer activity of pyrroloquinoline quinone (PQQ) [PDF]

Redox Report, 2010
Pyrroloquinoline quinone (PQQ), a bacterial redox co-factor and antioxidant, is highly reactive with nucleophilic compounds present in biological fluids. PQQ induced apoptosis in human promonocytic leukemia U937 cells and this was accompanied by depletion of the major cellular antioxidant glutathione and increase in intracellular reactive oxygen ...
Bhavani S, Shankar, Ruchi, Pandey, Prayag, Amin, Hari S, Misra, Krishna B, Sainis   +4 more
openaire   +2 more sources

Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. [PDF]

PLoS ONE, 2011
We have reported that pyrroloquinoline quinone (PQQ) improves reproduction, neonatal development, and mitochondrial function in animals by mechanisms that involve mitochondrial related cell signaling pathways.
Kathryn Bauerly, Calliandra Harris, Winyoo Chowanadisai, James Graham, Peter J Havel, Eskouhie Tchaparian, Mike Satre, Joel S Karliner, Robert B Rucker   +8 more
doaj   +1 more source

Comparative Effects of Pyrroloquinoline Quinone (PQQ) and Resveratrol (RSV) on Mitochondriogenesis in Mice

The FASEB Journal, 2021
Many phytochemicals and biofactors influence mitochondrial function, lipid deposition, and oxidative metabolism. Examples include phytoalexins, flavonoids, and quinones, such as PQQ. Herein, PQQ is compared to RSV (a phytoalexin).
R. Rucker, K. Jonscher, Winyoo Chowanadisai   +2 more
semanticscholar   +1 more source

Fabrication of pyrroloquinoline quinone-loaded small unilamellar vesicles through various downsizing techniques for biomedical applications

OpenNano
Treatment of injuries to bone structure represents a significant economic burden for health care institutions and systems worldwide. The development of tissue engineering scaffolds has expanded to include the incorporation of nanotechnology platforms ...
Gerardo Garcia-Zavaleta, Daniel Mejia-Valdez, Hamed Hosseinian, Ciro A. Rodriguez, Geoffrey A. Cordell, Yadira I. Vega-Cantu, Aida Rodriguez-Garcia   +6 more
doaj   +1 more source

Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway

Mediators of Inflammation, 2022
The current asthma therapies are inadequate for many patients with severe asthma. Pyrroloquinoline quinone (PQQ) is a naturally-occurring redox cofactor and nutrient that can exert a multitude of physiological effects, including anti-inflammatory and ...
Zhihui Min, Jiebai Zhou, Ruolin Mao, Bo Cui, Yunfeng Cheng, Zhihong Chen   +5 more
doaj   +1 more source

Biotransformation of Deoxynivalenol by a Dual-Member Bacterial Consortium Isolated from Tenebrio molitor Larval Feces

Toxins, 2023
In this study, a dual-member bacterial consortium with the ability to oxidize deoxynivalenol (DON) to 3-keto-DON, designated SD, was first screened from the feces of Tenebrio molitor larvae. This consortium consisted of Pseudomonas sp. SD17-1 and Devosia
Yang Wang, Donglei Zhao, Wei Zhang, Songxue Wang, Kai Huang, Baoyuan Guo   +5 more
doaj   +1 more source

Transcriptional regulation of insulin-degrading enzyme modulates mitochondrial amyloid β (Aβ) peptide catabolism and functionality [PDF]

, 2013
Studies of post-mortem brains from Alzheimer disease patients suggest that oxidative damage induced by mitochondrial amyloid β (mitAβ) accumulation is associated with mitochondrial dysfunction. However, the regulation of mitAβ metabolism is unknown.
Castaño, Eduardo Miguel, Evelson, Pablo Andres, Leal, Maria Celeste, Magnani, Natalia Daniela, Marino, Cristina Ester, Morelli, Laura, Villordo, Sergio   +6 more
core   +1 more source

A Glucose/O2 Biofuel Cell Using Recombinant Thermophilic Enzymes

International Journal of Electrochemical Science, 2012
The utilization of recombinant thermophilic enzymes to construct a glucose/O2 biofuel cell (BFC) workable in a wide temperature range with enhanced thermostability using thermophilic pyrroloquinoline quinone (PQQ) dependent glucose dehydrogenase (Tth ...
Xiuyun Wang, Dean Li, Tsuneaki Watanabe, Yasushi Shigemori, Tsutomu Mikawa, Takeyoshi Okajima, Lanqun Mao, Takeo Ohsaka   +7 more
doaj   +1 more source

Elektrogesponnene Polymerfasern als neuartiges Material für die Bioelektrokatalyse des Enzyms Pyrrolochinolinchinon-abhängige Glucosedehydrogenase [PDF]

, 2016
Es wurde ein dreidimensionales Polymerfasernetzwerk aufgebaut, charakterisiert und anschließend daran das Enzym Pyrrolochinolinchinon-abhängige Glukosedehydrogenase (PQQ)GDH gebunden. Das Polymerfasernetzwerk wurde durch Elektrospinnen einer Mischung des
Dietzel, Birgit, Gladisch, Johannes, Lisdat, Fred, Sarauli, David, Schulz, Burkhard, Schäfer, Daniel   +5 more
core   +1 more source

Pyrroloquinoline Quinone (PQQ) Nutritional Status in Humans after Oral Supplementation

The FASEB Journal, 2010
PQQ is a novel growth factor. Reproduction and mitochondrial metabolism are impaired in animals fed diets devoid of PQQ. However, little is known about PQQ functional parameters in humans. In a randomized study, 10 subjects ingested PQQ and were examined at daily/weekly intervals.
Calliandra Harris, Winyoo Chowanadisai, Michael Satre, Kathryn Bauerly, Kathryn Bauerly, Eskouhie Tchaparian   +5 more
openaire   +1 more source