Results 71 to 80 of about 28,371 (199)

A Periplasmic Binding Protein for Pyrroloquinoline Quinone

, 2019
Pyrroloquinoline quinone (PQQ) is an essential redox cofactor in bacterial calcium- and lanthanide-dependent alcohol dehydrogenases. Although certain bacteria are known to synthesize and secrete PQQ, little is known about trafficking of this cofactor ...
Jackson V. Ho (6750866), Joseph A. Cotruvo (2223247)   +1 more
core   +1 more source

Environmental Enrofloxacin Exposure as a Modifiable Driver of Mitochondria‐Mediated Intestinal Aging and Barrier Dysfunction

Aging Cell, Volume 25, Issue 5, May 2026.
Environmentally relevant enrofloxacin accelerates intestinal aging by impairing epithelial mitochondrial function, disrupting barrier integrity, and reshaping the gut microbiota. Mitochondrial restoration with pyrroloquinoline quinone alleviates hypoxia, inflammation, and gut damage.
Kan Yu, Nengzheng Wang, Xinyi Huang, Yushu Qiu, Xuejian He, Xiaofeng Zhu, Xiaolan Zhou, Peng Yu, Gang Wei, Yan Pi, Ting Ni   +10 more
wiley   +1 more source

Effect of dietary supplementation of pyrroloquinoline quinone disodium on growth performance, meat quality and antioxidative ability of broilers

Journal of Integrative Agriculture, 2020
This study was conducted to investigate the effect of dietary supplementation with pyrroloquinoline quinone (PQQ) in the form of PQQ disodium (PQQ▪Na2) on the growth performance, carcass traits, meat quality and antioxidative ability of broilers. A total
Guo-qing LIU, Guang-ming SUN, Xiu-dong LIAO, Jian-zhong HUANG, Mei-jin GUO, Li-yang ZHANG, Yan-li GUO, Lin LU, Xu-gang LUO   +8 more
doaj   +1 more source

Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway

Mediators of Inflammation, 2022
The current asthma therapies are inadequate for many patients with severe asthma. Pyrroloquinoline quinone (PQQ) is a naturally-occurring redox cofactor and nutrient that can exert a multitude of physiological effects, including anti-inflammatory and ...
Zhihui Min, Jiebai Zhou, Ruolin Mao, Bo Cui, Yunfeng Cheng, Zhihong Chen   +5 more
doaj   +1 more source

A Multicenter Trial of an Enhanced Serum Comprised of 13 Plant‐Based Adaptogens Targeting Skin Quality in Females Impacted by Hormonal Decline

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Objectives To assess the effectiveness and tolerability of a serum comprised of plant‐based adaptogens (MYS‐REV) for visible improvements in skin changes caused by hormonal fluctuations associated with perimenopause and postmenopause in women. Study Designs A 16‐week open‐label multicenter study evaluated the efficacy and tolerability of twice‐
Zoe D. Draelos, Amir Moradi, Amber Smathers   +2 more
wiley   +1 more source

Nephrotoxicity of Pyrroloquinoline Quinone in Rats [PDF]

, 1989
When pyrroloquinoline quinone (PQQ) was intraperitoneally injected into rats daily for 4 days at a dose of 11.5 mg/kg body weight/injection, functional and morphologic changes of the kidneys were clearly observed.
Tsuji, Takao, Hobara, Norio, Higashi, Toshihiro, Ohsawa, Toshiya, Watanabe, Akiharu   +4 more
core  

The pyrroloquinoline quinone biosynthesis pathway revisited: A structural approach [PDF]

, 2008
Background: The biosynthesis pathway of Pyrroloquinoline quinone, a bacterial redox active cofactor for numerous alcohol and aldose dehydrogenases, is largely unknown, but it is proven that at least six genes in Klebsiella pneumoniae (PqqA-F) are ...
Robert Schwarzenbacher, Puehringer, Sandra, Metlitzky, Moritz, Moritz Metlitzky, Schwarzenbacher, Robert, Sandra Puehringer   +5 more
core   +1 more source

Pyrroloquinoline Quinone Targets the Allosteric Activation Site of Nicotinamide Phosphoribosyltransferase (NAMPT): Structural Basis and Consequences for NAD⁺ Metabolism in Aging

Applied Sciences
NAD+ depletion is a defining feature of the aging cell, driven by a progressive decline in nicotinamide phosphoribosyltransferase (NAMPT) activity, the rate-limiting enzyme of the NAD+ salvage pathway.
Alessandro Medoro, Sergio Davinelli, Tassadaq Hussain Jafar, Truong Tan Trung, Ciro Costagliola, Gemma Caterina Maria Rossi, Giovanni Scapagnini   +6 more
doaj   +1 more source

Exploring Multifunctional Microbial Genes From the Rhizosphere of Allium ampeloprasum Under Different Fertilization Systems

Environmental DNA, Volume 8, Issue 2, March/April 2026.
This study uncovers key multifunctional genes in the rhizosphere of Allium ampeloprasum under varying fertilization systems. This highlights their roles in nutrient cycling, plant growth promotion, and soil health, thereby offering insight for sustainable agricultural sustainability.
Oluwaseun Emmanuel Shittu, Ben Jesuorsemwen Enagbonma, Olubukola Oluranti Babalola   +2 more
wiley   +1 more source

Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone

, 2004
The biosynthesis of pyrroloquinoline quinone (PQQ), a vitamin and redox cofactor of quinoprotein dehydrogenases, is facilitated by an unknown pathway that requires the expression of six genes, pqqA to -F.
Toyama, Hirohide, Magnusson, Olafur Th., Saeki, Megumi, Rojas Mendoza, Ana M., Klinman, Judith P., Liddington, Robert C., Schwarzenbacher, Robert, Reed, John C.   +7 more
core   +1 more source