Results 81 to 90 of about 23,834 (239)

Pyruvate Carboxylase [PDF]

Journal of Biological Chemistry, 1963
Merton F. Utter, Keech Db
openaire   +3 more sources

A simulation study on the role of mitochondria‐sarcoplasmic reticulum Ca2+ interaction in cardiomyocyte energetics during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend An integrated model of human ventricular myocyte with excitation‐contraction‐energetics coupling was created to systematically analyse the contribution of Ca2+ regulation of mitochondrial enzymes to cardiomyocyte functions during workload transition; i.e. exercise.
Ayako Takeuchi, Satoshi Matsuoka
wiley   +1 more source

Improvement of succinate production from methane by combining rational engineering and laboratory evolution in Methylomonas sp. DH-1

Microbial Cell Factories
Recently, methane has been considered a next-generation carbon feedstock due to its abundance and it is main component of shale gas and biogas. Methylomonas sp. DH-1 has been evaluated as a promising industrial bio-catalyst candidate.
Jae-Hwan Jo, Jeong-Ho Park, Byung Kwon Kim, Seon Jeong Kim, Chan Mi Park, Chang Keun Kang, Yong Jun Choi, Hyejin Kim, Eun Yeol Lee, Myounghoon Moon, Gwon Woo Park, Sangmin Lee, Soo Youn Lee, Jin-Suk Lee, Won-Heong Lee, Jeong-Il Kim, Min-Sik Kim   +16 more
doaj   +1 more source

Fructose catabolism and its metabolic effects: Exploring host–microbiota interactions and the impact of ethnicity

The Journal of Physiology, EarlyView.
Abstract figure legend This graphical abstract is a schematic representation highlighting the interactions between dietary fructose, gut microbiota and ethnicity in shaping metabolic health. Abstract Important health disparities are observed in the prevalence of obesity and associated non‐communicable diseases (NCDs), including type 2 diabetes (T2D ...
Florine H.M. Westerbeke, Melany Rios‐Morales, Ilias Attaye, Max Nieuwdorp   +3 more
wiley   +1 more source

Spectrometry and Its Application for the Detection of RNA‐Binding Proteins: Advancements, Techniques and Challenges

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT Spectrometry is a fascinating field of analytical science that encompasses a range of techniques used to study the interaction between electromagnetic radiation and matter. Through the measurement and analysis of various radiations, spectrometry provides valuable insights into the composition, structure and properties of different substances ...
Mina Moradi, Zahra Farjami, Mohammad Mehdi Akbarin   +2 more
wiley   +1 more source

Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1Research in Context

EBioMedicine, 2018
Background: Mitochondrial pyruvate import via mitochondrial pyruvate carrier (MPC) is a central step in hepatic gluconeogenesis. Berberine inhibits hepatic gluconeogenesis, but the mechanism is incompletely understood.
Aiyun Li, Qun Liu, Qiang Li, Baolin Liu, Yang Yang, Ning Zhang   +5 more
doaj  

Multi‐omic data integration and exploiting metabolic models using systems biology approach increase precision in subtyping and early diagnosis of cancer

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cancer is a complex and heterogeneous disease characterized by various genetic and epigenetic alterations. Early diagnosis, accurate subtyping, and staging are essential for effective, personalized treatment and improved survival rates. Traditional diagnostic methods, such as biopsies, are invasive and carry operational risks that hinder ...
Ezgi Tanıl, Emrah Nikerel
wiley   +1 more source

Metabolic responses of primary and transformed cells to intracellular Listeria monocytogenes.

PLoS ONE, 2012
The metabolic response of host cells, in particular of primary mammalian cells, to bacterial infections is poorly understood. Here, we compare the carbon metabolism of primary mouse macrophages and of established J774A.1 cells upon Listeria monocytogenes
Nadine Gillmaier, Andreas Götz, Anette Schulz, Wolfgang Eisenreich, Werner Goebel   +4 more
doaj   +1 more source

Phosphoenolpyruvate carboxykinase and pyruvate carboxylase in developing rat liver [PDF]

, 1967
F J Ballard, RW Hanson
openalex   +1 more source

Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Senescent tumor cells in TME exhibit dual roles. “Angels” secrete SASPs/DAMPs to boost immunological clearance and antitumor immunity via MHC‐I upregulation; “Demons” produce tumor‐promoting SASPs recruiting MDSCs to drive malignancy. ABSTRACT Cellular senescence, a state of irreversible cell cycle arrest accompanied by a senescence‐associated ...
Jingrui Yan, Yu Zhang, Guohua Mao, Jun Yu, Tianxing Zhou, Jihui Hao   +5 more
wiley   +1 more source