Results 131 to 140 of about 96,844 (281)

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Perioperative considerations of pyruvate dehydrogenase complex deficiency: a case report of two consecutive anesthesia. [PDF]

Anesth Pain Med (Seoul), 2023
Lim WY, Lee HJ, Park EJ, Jeon S, Do W, Kim HJ, Lee D, Hong JM.   +7 more
europepmc   +1 more source

Activity oscillations predicted for pyruvate dehydrogenase complexes

, 1994
A kinetic model for the pyruvate dehydrogenase complex is analyzed. The model takes into account intermediate channeling through the lipoyl network attached to the complex core, as well as inter-related regulatory effects of protein X acetylation and ...
Zakrzhevskaya, D.T., B.N. Goldstein, Goldstein, B.N., Selivanov, V.A., D.T. Zakrzhevskaya, V.A. Selivanov   +5 more
core   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

USP39 regulates pyruvate handling in non-small cell lung cancer

Cell Death Discovery
The ubiquitin-specific peptidase 39 (USP39) belongs to the USP family of cysteine proteases representing the largest group of human deubiquitinases (DUBs).
Tina Becirovic, Boxi Zhang, Helin Vakifahmetoglu-Norberg, Vitaliy O. Kaminskyy, Elena Kochetkova, Erik Norberg   +5 more
doaj   +1 more source

Pyruvate Dehydrogenase Complex and Glucose Oxidation as a Therapeutic Target in Diabetic Heart Disease. [PDF]

J Lipid Atheroscler, 2023
Tabatabaei Dakhili SA, Greenwell AA, Ussher JR.   +2 more
europepmc   +1 more source

Effects of Guanidine Hydrochloride on Pyruvate Dehydrogenase Complex 

, 2002
Many molecules of pyruvate decarboxylase （E1） and dihydrolipoamide dehydrogenase （E3） bind non-covalently to a sixty-meric lipoate acetyltransferase （E2）, forming the Bacillus stearothermophilus pyruvate dehydrogenase complex.
Aso, Yoichi, Meno, Kohji, Hiromasa, Yasuaki, Ishiguro, Masatsune, Kita, Masahito, 石黒, 正恒, 麻生, 陽一, Irie, Toshiro   +7 more
core  

Electroenzymatic CO2 Fixation

Angewandte Chemie International Edition, EarlyView.
Electroenzymatic CO2 fixation enables energy‐efficient, highly selective synthesis of complex molecules. Unlocking its full potential requires fundamental understanding of electrode‐coupled reductases and carboxylases. This review critically discusses available enzymes, product scope, and key thermodynamic and kinetic considerations, highlighting ...
Leonardo Castañeda‐Losada, Michael Richter, Christophe Léger, Vincent Fourmond, Nicolas Plumeré   +4 more
wiley   +1 more source

Human Serum Mediated Bacteriophage Life Cycle Switch in Aggregatibacter actinomycetemcomitans Is Linked to Pyruvate Dehydrogenase Complex. [PDF]

Life (Basel), 2023
Tang-Siegel GG.
europepmc   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source