Results 141 to 150 of about 94,657 (246)

Stoichiometry and architecture of the human pyruvate dehydrogenase complex. [PDF]

Sci Adv
Zdanowicz R, Afanasyev P, Pruška A, Harrison JA, Giese C, Boehringer D, Leitner A, Zenobi R, Glockshuber R.   +8 more
europepmc   +1 more source

Plastidic pyruvate dehydrogenase complex E1 component subunit Alpha1 is involved in galactolipid biosynthesis required for amyloplast development in rice. [PDF]

Plant Biotechnol J, 2022
Lei J, Teng X, Wang Y, Jiang X, Zhao H, Zheng X, Ren Y, Dong H, Wang Y, Duan E, Zhang Y, Zhang W, Yang H, Chen X, Chen R, Zhang Y, Yu M, Xu S, Bao X, Zhang P, Liu S, Liu X, Tian Y, Jiang L, Wang Y, Wan J.   +25 more
europepmc   +1 more source

Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Genetic mitochondrial diseases (GMDs) are a large group of genetically and clinically heterogeneous disorders caused by defects in genes encoding mitochondrial components. GMDs are grouped into named syndromes based on clinical presentation, for example, Leigh syndrome (LS).
Brittany M. Johnson, Simon C. Johnson
wiley   +1 more source

Histone acetyltransferase HAF2 associates with pyruvate dehydrogenase complex to control H3K14ac and H3K23ac in ethylene response. [PDF]

Cell Rep
Chen CY, Shao Z, Wang G, Zhao B, Hardtke HA, Leong J, Zhou T, Zhang YJ, Qiao H.   +8 more
europepmc   +1 more source

TGF-β1 is a regulator of the pyruvate dehydrogenase complex in fibroblasts. [PDF]

Sci Rep, 2020
Smith ER, Hewitson TD.
europepmc   +1 more source

CCL5 and GLUT1 define leader cells in collective invasion of colorectal cancer

The Journal of Pathology, EarlyView.
Abstract Invasion and metastasis in multiple solid tumors are promoted by collective invasion which is organized by leader and follower cells. Yet in colorectal cancer (CRC), biomarkers and mechanisms that specify leader cells remain undefined. Here we identify biomarkers of leader cells and elucidate how they drive CRC collective invasion and ...
Zhaowen Zhang, Jiaying Tan, Zhicheng Zeng, Xiaohui Zhu, Liyao Mai, Yao Yin, Yuting Huang, Wei Kang, Honghui Jiang, Shaowan Xu, Yanqing Ding, Xinghua Pan, Feifei Wang, Li Liang   +13 more
wiley   +1 more source

Comparative Analysis of Symmetry Parameters in the E2 Inner Core of the Pyruvate Dehydrogenase Complex. [PDF]

Int J Mol Sci
Kim HU, Jeong MS, An MY, Park YH, Park SH, Chung SJ, Yi YS, Jun S, Kim YK, Jung HS.   +9 more
europepmc   +1 more source

Photoactivated iridium(III) complexes drive pyroptosis–necroptosis synergy for multi‐network photoimmunotherapy of renal cell carcinoma

Smart Molecules, EarlyView.
Photoactivated iridium(III) complexes trigger mitochondrial DNA leakage and Ca²⁺ efflux, simultaneously driving pyroptosis and necroptosis to synergistically enhance immunogenic cell death. This multi‐network cascade promotes dendritic cell maturation and CD8⁺ T cell activation, achieving potent photoimmunotherapy of renal cell carcinoma.
Xin Qin, Meng‐Di Chen, Wenqi Gao, Yiping Wang, Lin‐Qing Liu, Zhen Teng, Tienan Qi, Qiyuan Wang, Yuxuan Wang, Daoxiang Li, Keqiang Yan, Ling Pan, Zhongwei Zhao, Shuo Zhao, Kang‐Nan Wang, Shuai Fu, Nengwang Yu   +16 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Pyruvate Dehydrogenase Complex in Neonatal Hypoxic-Ischemic Brain Injury. [PDF]

ACS Pharmacol Transl Sci
Zhou T, Zhong Y, Zhang Y, Zhou Y.
europepmc   +1 more source