Results 171 to 180 of about 96,844 (281)

Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion

The pyruvate dehydrogenase complex (PDHc) links glycolysis to the citric acid cycle by converting pyruvate into acetyl-coenzyme A. PDHc encompasses three enzymatically active subunits, namely pyruvate dehydrogenase, dihydrolipoyl transacetylase, and ...
Berndtsson, Jens,, Stenmark, Pål,, Ott, Martin,, Nolte, Hendrik, Škerlová, Jana,   +4 more
core  

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source

Dynamics of the mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis. [PDF]

Nat Commun
Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y.   +16 more
europepmc   +1 more source

Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells. [PDF]

Eng Life Sci, 2021
Möller J, Bhat K, Guhl L, Pörtner R, Jandt U, Zeng AP.   +5 more
europepmc   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

Epilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer, Chiara A. Hummel, Tobias Baumgartner, Juliane L. Berns, Afaf Milad Said, Isabel Bünger, Susanne Schoch, Gábor Zsurka, Harald Prüss, Wolfram S. Kunz, Rainer Surges, Albert J. Becker, Julika Pitsch   +12 more
wiley   +1 more source

Stoichiometry and architecture of the human pyruvate dehydrogenase complex. [PDF]

Sci Adv
Zdanowicz R, Afanasyev P, Pruška A, Harrison JA, Giese C, Boehringer D, Leitner A, Zenobi R, Glockshuber R.   +8 more
europepmc   +1 more source

Plastidic pyruvate dehydrogenase complex E1 component subunit Alpha1 is involved in galactolipid biosynthesis required for amyloplast development in rice. [PDF]

Plant Biotechnol J, 2022
Lei J, Teng X, Wang Y, Jiang X, Zhao H, Zheng X, Ren Y, Dong H, Wang Y, Duan E, Zhang Y, Zhang W, Yang H, Chen X, Chen R, Zhang Y, Yu M, Xu S, Bao X, Zhang P, Liu S, Liu X, Tian Y, Jiang L, Wang Y, Wan J.   +25 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Histone acetyltransferase HAF2 associates with pyruvate dehydrogenase complex to control H3K14ac and H3K23ac in ethylene response. [PDF]

Cell Rep
Chen CY, Shao Z, Wang G, Zhao B, Hardtke HA, Leong J, Zhou T, Zhang YJ, Qiao H.   +8 more
europepmc   +1 more source

TGF-β1 is a regulator of the pyruvate dehydrogenase complex in fibroblasts. [PDF]

Sci Rep, 2020
Smith ER, Hewitson TD.
europepmc   +1 more source