Results 211 to 220 of about 140,469 (257)

[68] Pyruvate dehydrogenase complex from Bacillus

1982
Publisher Summary The pyruvate dehydrogenase complex is a multienzyme complex catalyzing the oxidative decarboxylation of pyruvate to acetyl coenzyme (CoA). This chapter describes the assay method and properties of pyruvate dehydrogenase complex isolated from Bacillus .
Visser, J., Kester, H.C.M., Jeyaseelan, K., Topp, R.   +3 more
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The Pyruvate Dehydrogenase Multienzyme Complex

Angewandte Chemie International Edition in English, 1975
AbstractThe three enzymes pyruvate dehydrogenase, dihydrolipoamide transacetylase, and dihydrolipoamide dehydrogenase constitute the pyruvate dehydrogenase multienzyme complex of E. coli; in mammals the complex also contains a kinase and a phosphatase.
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The pyruvate dehydrogenase complex during aging

Mechanisms of Ageing and Development, 1984
Acetylcholine synthesis and pyruvate oxidation decline with age. To determine the role of the pyruvate dehydrogenase complex in these age-related deficits, its activity and activation state were measured in vivo and in vitro in the brains of 3-, 10- and 30-month-old mice.
Christine Peterson, Gary E. Gibson, Hanna Ksiezak-Reding   +2 more
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The hormonal regulation of pyruvate dehydrogenase complex

Advances in Enzyme Regulation, 1996
The pyruvate dehydrogenase complex has a central role in the regulation of mammalian metabolism as it represents the point-of-no-return in the utilization of carbohydrate. This article summarizes our studies into how signalling systems initiated by hormones binding to cell surface receptors can reach the pyruvate dehydrogenase system which is located ...
Denton, RM, McCormack, JG, Rutter, GA, Burnett, Paul, Edgell, NJ, Moule, SK, Diggle, TA   +6 more
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Pyruvate Dehydrogenase Complex Deficiency

2006
Abstract Identical twins with the fictitious names Ann and Elizabeth were born 6 weeks prematurely to a healthy 26-year-old mother whose pregnancy was uneventful. The family history was noteworthy for epilepsy in a paternal aunt, congenital deafness in another paternal aunt, and possible mental retardation in a maternal cousin. The twins’
Peter W Stacpoole, Lesa R Gilbert
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Plant pyruvate dehydrogenase complexes

1996
While there is considerable overall metabolic similarity between plant and animal cells, drastically different anatomy, physiology, and organismal requirements have led to increasing diversity between these two classes of eukaryotes. Analyses of the pyruvate dehydrogenase complex (PDC) in plant cells serve to illustrate both the similarities inherent ...
Michael H. Luethy, Jan A. Miernyk, Douglas D. Randall, Nancy R. David   +3 more
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Pyruvate Dehydrogenase Complex

1969
Publisher Summary This chapter discusses the multienzyme pyruvate dehydrogenase complexes, with emphasis on their structure, function, and regulation. These complexes have been isolated from Escherichia coli and from animal tissues as functional units with molecular weights in the millions.
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Pyruvate Dehydrogenase Complex Deficiencies

2012
Pyruvate dehydrogenase complex (PDC) deficiencies, affecting a critical step in carbohydrate oxidative metabolism, have heterogeneous genetic causes and outcomes. There are few correlations between numerous mutations, affecting at least 10 genes, measured PDC enzyme activity, and the clinical outcome. The presentation varies by age and sex.
Douglas S. Kerr, Suzanne D. DeBrosse
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Fluorescent derivatives of the pyruvate dehydrogenase component of the Escherichia coli pyruvate dehydrogenase complex

Biochemistry, 1977
One sulfhydryl group per polypeptide chain of the pyruvate dehydrogenase component of the pyruvate dehydrogenase multienzyme complex from Escherichia coli was selectively labeled with N-[P-(2-benzoxazoyl)phenyl]-maleimide (NBM), 4-dimethylamino-4-magnitude of-maleimidostilbene (NSM), and N-(4-dimethylamino-3,5-dinitrophenyl)maleimide (DDPM) in 0.05 M ...
Gordon G. Hammes, Nicholas Papadakis
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Effect of mycoplasma infection on pyruvate dehydrogenase complex activity of normal and pyruvate dehydrogenase complex-deficient fibroblasts

Experimental Cell Research, 1984
The fermentative mycoplasmas A. laidlawii JS, M. hyorhinis DBS-50, M. hyorhinis GDL and M. pneumoniae FH have very high apparent activities of pyruvate dehydrogenase (PDH) (EC 1.2.4.1) and pyruvate dehydrogenase complex (PDHC). Infection of normal and PDHC-deficient fibroblasts with these mycoplasma species resulted in a marked increase of the specific
G.J. McGarrity, George Constantopoulos, John A. Barranger   +2 more
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