Results 291 to 300 of about 168,834 (385)

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

, 2009
Lin Piao, Yong-Hu Fang, Virgilio J. J. Cadete, Christian Wietholt, Dalia Urboniene, Péter T. Tóth, Glenn Marsboom, Hannah J. Zhang, Idith Haber, Jalees Rehman, Gary D. Lopaschuk, Stephen L. Archer   +11 more
openalex   +2 more sources

Remodeling of the terpenoid metabolism during prolonged phosphate depletion in the marine diatom Phaeodactylum tricornutum

Journal of Phycology, EarlyView.
Abstract Terpenoids are a diverse class of naturally occurring organic compounds, which derive from five‐carbon isoprene units and play crucial roles in physiology, ecological interactions such as defense mechanisms, or adaptation to environmental stresses.
Florian Pruckner, Luca Morelli, Payal Patwari, Michele Fabris   +3 more
wiley   +1 more source

Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review

Journal of Periodontal Research, EarlyView.
Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana, Giacomo Baima, Giovanni Iaderosa, Francesco Franco, Jianjian Zhang, Giovanni Nicolao Berta, Federica Romano, Mario Aimetti   +7 more
wiley   +1 more source

At‐RS31 orchestrates hierarchical cross‐regulation of splicing factors and integrates alternative splicing with TOR‐ABA pathways

New Phytologist, EarlyView.
Summary Alternative splicing is essential for plants, enabling a single gene to produce multiple transcript variants to boost functional diversity and fine‐tune responses to environmental and developmental cues. Arabidopsis thaliana At‐RS31, a plant‐specific splicing factor in the Serine/Arginine‐rich (SR) protein family, responds to light and the ...
Tino Köster, Peter Venhuizen, Martin Lewinski, Ezequiel Petrillo, Yamile Marquez, Armin Fuchs, Debashish Ray, Barbara A. Nimeth, Stefan Riegler, Sophie Franzmeier, Florencia S. Rodríguez, Federico E. Aballay, Rocío S. Tognacca, Hong Zheng, Timothy Hughes, Quaid Morris, Andrea Barta, Dorothee Staiger, Maria Kalyna   +18 more
wiley   +1 more source

Targeting Hypoxia‐Inducible Factor‐1&agr;/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin‐induced Pulmonary Fibrosis

American Journal of Respiratory Cell and Molecular Biology, 2017
Justin Goodwin, Hyunsung Choi, Meng-Hsiung Hsieh, Michael L. Neugent, Jung-Mo Ahn, Heather N. Hayenga, P. Singh, D. Shackelford, In-kyu Lee, V. Shulaev, S. Dhar, Norihiko Takeda, Jung-whan Kim   +12 more
semanticscholar   +1 more source

Pollution, stress response, and obesity: A systematic review

Obesity Reviews, Volume 26, Issue 5, May 2025.
Summary Limited literature addresses the association between pollution, stress, and obesity, and knowledge synthesis on the associations between these three topics has yet to be made. Two reviewers independently conducted a systematic review of MEDLINE, Embase, and Web of Science Core Collection databases to identify studies dealing with the effects of
Sandra El Kouche, Sarah Halvick, Chloe Morel, Radu‐Corneliu Duca, An van Nieuwenhuyse, Jonathan D. Turner, Nathalie Grova, David Meyre   +7 more
wiley   +1 more source

Pyruvate dehydrogenase kinase I knock down in INS-1 832/13 Cells enhances insulin secretion and the cellular NADPH/NADP(+) ratio [PDF]

, 2008
Olga Kotova, Ulrika Krus, M C Sugden, Hindrik Mulder   +3 more
openalex  

Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth

Plant Biotechnology Journal, Volume 23, Issue 4, Page 1230-1242, April 2025.
Summary The first step in chloroplast de novo fatty acid synthesis is catalysed by acetyl‐CoA carboxylase (ACCase). As the rate‐limiting step for this pathway, ACCase is subject to both positive and negative regulation. In this study, we identify a Chlamydomonas homologue of the plant carboxyltransferase interactor 1 (CrCTI1) and show that this protein
Zhongze Li, Minjae Kim, Jose Roberto da Silva Nascimento, Bertrand Legeret, Gabriel Lemes Jorge, Marie Bertrand, Fred Beisson, Jay J. Thelen, Yonghua Li‐Beisson   +8 more
wiley   +1 more source

Flicking the Warburg Switch—Tyrosine Phosphorylation of Pyruvate Dehydrogenase Kinase Regulates Mitochondrial Activity in Cancer Cells

, 2011
Almut Schulze, Julian Downward
openalex   +1 more source

Pyruvate Dehydrogenase Kinase 1 Participates in Macrophage Polarization via Regulating Glucose Metabolism

Journal of Immunology, 2015
Zheng Tan, N. Xie, H. Cui, D. Moellering, E. Abraham, V. Thannickal, Gang Liu   +6 more
semanticscholar   +1 more source