Results 201 to 210 of about 240,985 (333)

Modulation of Malaria Phenotypes by Pyruvate Kinase (PKLR) Variants in a Thai Population

, 2015
Rebekah van Bruggen, Christian O. Gualtieri, Alexandra Iliescu, Chalisa Louicharoen Cheepsunthorn, Punchalee Mungkalasut, Jean‐François Trape, David Modiano, Sodiomon B. Sirima, Pratap Singhasivanon, Mark Lathrop, Anavaj Sakuntabhai, Jean‐François Bureau, Philippe Gros   +12 more
openalex   +2 more sources

Phosphoenolpyruvate carboxylase kinase involved in C₄ photosynthesis in Flaveria trinervia: cDNA cloning and characterization¹ [PDF]

, 2001
Yuhei Tsuchida, Tsuyoshi Furumoto, Atsushi Izumida, Shingo Hata, Katsura Izui   +4 more
openalex   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Potent Fluorescent Probe for Target-Engagement Studies of Allosteric Pyruvate Kinase Modulators. [PDF]

Angew Chem Int Ed Engl
Nilsson O, Valaka AP, Håversen L, Bogucka A, Köteles I, Brear P, Rutberg M, Gunnarsson A, Hyvönen M, Grøtli M.   +9 more
europepmc   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Comparison of docking procedures and its efficiency for Betasecretase, Aromatase and Pyruvate dehydrogenase kinase inhibitors

, 2017
Zahra Rezaei, Masood Fereidoonnezhad, Zeinab Faghih, Hossein Sadeghpur, Ayyub Mojaddami, Amirhossein Sakhteman   +5 more
openalex   +2 more sources

Enhanced deoxyviolacein bioproduction via enzyme condensation with a yeast glycolytic enzyme‐derived peptide tag

Biotechnology Progress, EarlyView.
Fusion of a 27‐amino‐acid peptide tag derived from a glycolytic enzyme enabled artificial assembly formation of the two violacein biosynthetic enzymes, VioE and VioC. This assembly resulted in enhanced biosynthesis of deoxyviolacein. Abstract In microbial production, regulating endogenous and exogenous synthetic pathways is essential.
Rioko Ito, Sayoko Ito‐Harashima, Naoko Segawa, Natsuko Miura, Michihiko Kataoka   +4 more
wiley   +1 more source

Pyruvate kinase M2 promotes venous thrombosis by enhancing SNAP23-mediated platelet exocytosis and consequent NETosis. [PDF]

Blood Adv
Nayak MK, Flora GD, Budnik I, Barbhuyan T, Patel RB, Ghatge M, Kumskova M, Jain A, Chauhan N, Kumar J, Jewell M, Kumar S, Lentz SR, Neeves KB, Chauhan AK.   +14 more
europepmc   +1 more source

Studies on the dietary regulation of jejunal pyruvate kinase and sucrase activities [PDF]

, 1971
Reuben S. Dubois, Ronald W. Gotlin, Denis O. Rodgerson, Donough OʼBrien   +3 more
openalex   +1 more source

Dynamics of natural killer cell function upon recurrent stimulation

Biotechnology Progress, EarlyView.
Weekly stimulation of peripheral blood‐derived NK cells with engineered K562 feeder cells resulted in two distinct growth phases, shifting around Day 21–26. Cells in growth phase 2 exhibited slower growth, reduced metabolic activity, and lower cytotoxicity than cells from growth phase 1, which has implications for NK cell biomanufacturing.
Jennifer One, Janani Narayan, Frank Cichocki, Wei‐Shou Hu, Samira M. Azarin   +4 more
wiley   +1 more source