Results 201 to 210 of about 234,539 (335)

The Functional State of <i>Thermoplasma acidophilum</i> Pyruvate Kinase Relies on an Extra Carboxyl-Terminal Sequence. [PDF]

Int J Mol Sci
Ramírez-Silva L, Riveros-Rosas H, Hernández-Alcántara G, García-Trejo JJ, Vega-Segura A, González-Andrade M, Díaz-Salazar AJ, Salcedo-Barrientos G.   +7 more
europepmc   +1 more source

Inactivation of Tetrameric Rabbit Muscle Pyruvate Kinase by Specific Binding of 2 to 4 Moles of Pyridoxal 5'-Phosphate

, 1970
George S. Johnson, William C. Deal
openalex   +1 more source

Succinic Acid Production by Engineered Mannheimia succiniciproducens and Its Use in Chemoenzymatic Poly(Butylene Succinate) Synthesis

Biotechnology and Bioengineering, EarlyView.
Succinic acid is produced by the fermentation of metabolically engineered Mannheimia succiniciproducens, purified, and used to synthesize poly(butylene succinate) using a two‐step process that involves the esterification of succinic acid and ethanol, followed by enzymatic transesterification of diethyl succinate and 1,4‐butanediol.
Ji Yeon Kim, Jong An Lee, Gi Bae Kim, Youngjoon Lee, Sang Yup Lee   +4 more
wiley   +1 more source

Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression. [PDF]

Mol Biomed
Zhao K, Zhang F, Qin Q, Zhang D, Yang F, Huang Y, Deng R, Jing H, Xiao W, Miao H, Shi R.   +10 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection. [PDF]

Mol Metab
Waller TJ, Collins CA, Dus M.
europepmc   +1 more source

Enhanced deoxyviolacein bioproduction via enzyme condensation with a yeast glycolytic enzyme‐derived peptide tag

Biotechnology Progress, EarlyView.
Fusion of a 27‐amino‐acid peptide tag derived from a glycolytic enzyme enabled artificial assembly formation of the two violacein biosynthetic enzymes, VioE and VioC. This assembly resulted in enhanced biosynthesis of deoxyviolacein. Abstract In microbial production, regulating endogenous and exogenous synthetic pathways is essential.
Rioko Ito, Sayoko Ito‐Harashima, Naoko Segawa, Natsuko Miura, Michihiko Kataoka   +4 more
wiley   +1 more source

Maximum activities and effects of fructose bisphosphate on pyruvate kinase from muscles of vertebrates and invertebrates in relation to the control of glycolysis [PDF]

, 1978
Victor A. Zammit, Isidorus Beis, Eric A. Newsholme   +2 more
openalex   +1 more source

Lactylation in cancer biology: Unlocking new avenues for research and therapy

Cancer Communications, EarlyView.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou, Zhenya Hong, Huimin Zeng, Changyi Zhang, Peng Zhang, Ding Ma, Zhiqiang Han   +6 more
wiley   +1 more source

Pyruvate Kinase Deficiency: Markedly Decreased Reticulocyte PK Activity and Limited Specificity of the PK/HK Ratio. [PDF]

Int J Mol Sci
Koleva L, Dolgikh IA, Kryukova AV, Prudinnik DS, Bovt EA, Shakhidzhanov SS, Mann SG, Smetanina NS, Ataullakhanov FI, Sinauridze EI.   +9 more
europepmc   +1 more source