Results 201 to 210 of about 128,438 (311)

Electrophoretic, immunologic and kinetic characterization of erythrocyte pyruvate kinase in the basenji dog with pyruvate kinase deficiency.

, 1975
Koji Nakashima, Shiro Miwa, Kenji Shinohara, Etsuko Oda, Mitsuaki Tajiri, Shigenobu ABE, Junichiro Ono, John A. Black   +7 more
openalex   +2 more sources

Gut Microbiota‐Associated Metabolites Affected the Susceptibility to Heart Health Abnormality in Young Migrants at High‐Altitude

Exploration, EarlyView.
Long‐term migration to high‐altitude areas can readily result in chronic high‐altitude diseases; however, effective prevention and treatment methods are currently lacking. This study employed a multi‐omics approach, integrating metagenomics and metabolomics, to discover and validate that the decreased abundance of Veillonella rogosae, Streptococcus ...
Yongqiang Zhou, Zhexin Ni, Jingjing Liu, Dezhi Sun, Pan Shen, Xi Chen, Gaofu Li, Zhijie Bai, Yangyi Hu, Ningning Wang, Rui Wang, Lina Guan, Yihao Wang, Xianglin Tang, Yungang Lu, Baokun He, Haitao Lu, Wei Zhou, Yue Gao   +18 more
wiley   +1 more source

Targeting pyruvate kinase M2 for the treatment of kidney disease. [PDF]

Front Pharmacol
Chen DQ, Han J, Liu H, Feng K, Li P.
europepmc   +1 more source

Corynebacterium glutamicum for Microbial Production of Chitin Oligosaccharides Using Modular Engineering

Food Bioengineering, EarlyView.
Based on metabolic engineering, a chitin oligosaccharide (CHOSs) synthesis metabolic pathway was constructed in Corynebacterium glutamicum, establishing a cell factory for CHOSs synthesis through the selection of chassis cells and key enzymes. Utilizing this framework, multiple strategies were employed to enhance the GlcNAc and UDP‐GlcNAc synthesis ...
Chen Deng, Ruijie Xin, Xingjian Li, Liqiang Fan, Yongjun Qiu, Liming Zhao   +5 more
wiley   +1 more source

Podocyte SIRPα reduction in diabetic nephropathy aggravates podocyte injury by promoting pyruvate kinase M2 nuclear translocation. [PDF]

Redox Biol
Chen Y, Zhang M, Jia R, Qian B, Jing C, Zeng C, Zhu D, Liu Z, Zen K, Li L.   +9 more
europepmc   +1 more source

Oat Bran Supplementation Improves Glucose Metabolism, Food Addiction, and Gut Microbiota in Rats With High‐Fat Diet‐Induced Obesity

Food Frontiers, EarlyView.
ABSTRACT Oat bran (OB), a byproduct of the oat milling process, is a nutrient‐dense cereal cultivated in cool, dry mountainous regions and is known for its potential health benefits. To explore its obesity‐alleviating effects and the underlying mechanisms, we examined the influence of OB on glucose metabolism, appetite‐regulating hormones, gut ...
Xue Bai, Meili Zhang, Yakun Zhang, Yuanyuan Zhang, Rui Huo, Qixin Gu, Ying Miao   +6 more
wiley   +1 more source

Response to Mitapivat: A Quinolone Sulfonamide to Manage Hemolytic Anemia in Adults With Pyruvate Kinase Deficiency. [PDF]

Am J Ther
Boscoe A, McCracken R, Marathe P, Osman K.   +3 more
europepmc   +1 more source

The reversibility of skeletal muscle pyruvate kinase and an assessment of its capacity to support glyconeogenesis.

, 1975
RD Dyson, JM Cardenas, RJ Barsotti
openalex   +1 more source

Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection

Glia, EarlyView.
Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa, Jose L. Martin, Arzu Ulu, William Agnew‐Svoboda, Teresa Ubina, Martin M. Riccomagno, Todd A. Fiacco, Emma H. Wilson   +7 more
wiley   +1 more source

The Efficacy of Mitapivat in Case of Transfusion Dependence Linked to Beta Thalassemia Trait Associated with Pyruvate Kinase Deficiency. [PDF]

J Cell Mol Med
Fatigati C, Costantini S, Spasiano A, Ziello B, Gambale A, Ricchi P.   +5 more
europepmc   +1 more source