Results 201 to 210 of about 1,270,348 (335)

Potent Fluorescent Probe for Target-Engagement Studies of Allosteric Pyruvate Kinase Modulators. [PDF]

Angew Chem Int Ed Engl
Nilsson O, Valaka AP, Håversen L, Bogucka A, Köteles I, Brear P, Rutberg M, Gunnarsson A, Hyvönen M, Grøtli M.   +9 more
europepmc   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

An Optimized Enzyme-Coupled Spectrophotometric Method for Measuring Pyruvate Kinase Kinetics. [PDF]

Bio Protoc
Upadhyay S.
europepmc   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Pyruvate kinase M2 promotes venous thrombosis by enhancing SNAP23-mediated platelet exocytosis and consequent NETosis. [PDF]

Blood Adv
Nayak MK, Flora GD, Budnik I, Barbhuyan T, Patel RB, Ghatge M, Kumskova M, Jain A, Chauhan N, Kumar J, Jewell M, Kumar S, Lentz SR, Neeves KB, Chauhan AK.   +14 more
europepmc   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Pyruvate kinase M2 modulates Japanese encephalitis virus replication in neuronal cells. [PDF]

J Gen Virol
Bohara VS, Deshmukh A, Kumar S.
europepmc   +1 more source

Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis.

Cell Metabolism, 2018
Xinshou Ouyang, Sheng-Na Han, Jiyuan Zhang, E. Dioletis, B. Németh, P. Pacher, D. Feng, R. Bataller, J. Cabezas, P. Stärkel, J. Caballería, Rebecca L. Pongratz, Shi-Ying Cai, B. Schnabl, Rafaz Hoque, Yonglin Chen, Wei-hong Yang, Irma Garcia-Martinez, Fu-Sheng Wang, B. Gao, Natalie J. Torok, R. Kibbey, W. Mehal   +22 more
semanticscholar   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Bovine Pyruvate Kinases

Journal of Biological Chemistry, 1973
Janet M. Cardenas, Robert D. Dyson, J. Jeffrey Strandholm   +2 more
openaire   +2 more sources