Results 271 to 280 of about 1,722,299 (336)

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells. [PDF]

Cell Commun Signal
Matesanz-Sánchez R, Classen S, Siniuk K, Peitzsch M, Alves T, Pospiech H, Borgmann K, Cordes N.   +7 more
europepmc   +1 more source

[Pyruvate kinase].

Postepy higieny i medycyny doswiadczalnej, 1987
openaire   +1 more source

Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion. [PDF]

FASEB J
Murao N, Morikawa R, Seino Y, Shimomura K, Maejima Y, Ohno T, Yokoi N, Yamada Y, Suzuki A.   +8 more
europepmc   +1 more source

Genome-Wide Identification and Expression Profiling of Pyruvate Kinase Genes in Litchi Under Calcium-Magnesium Foliar Treatment. [PDF]

Plants (Basel)
Sajjad M, Jiao J, Tahir H, Wei L, Ma W, Zeeshan Ul Haq M, Farooq MA, Zhou K.   +7 more
europepmc   +1 more source

Transcriptomic analysis reveals that pyruvate kinase potentially plays a key role in the differentiation of Spirometra mansoni proglottids by regulating the glycolysis pathway. [PDF]

PLoS Negl Trop Dis
Zhou K, Cao CY, Ru SS, Wang RJ, Hao J, Zhang X.   +5 more
europepmc   +1 more source

Correction to "Pyruvate Kinase Function Correlates With Red Blood Cell Properties and Clinical Manifestations in Sickle Cell Disease". [PDF]

Am J Hematol
europepmc   +1 more source

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Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy

Biochimica Et Biophysica Acta: Reviews on Cancer, 2021
Pyruvate is irreversibly decarboxylated to acetyl coenzyme A by mitochondrial pyruvate dehydrogenase complex (PDC). Decarboxylation of pyruvate is considered a crucial step in cell metabolism and energetics.
Anas Shamsi, Asimul Islam, Taj Mohammad
exaly   +2 more sources

Pyruvate kinase M2 (PKM2) in cancer and cancer therapeutics.

Cancer Letters, 2020
Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, is a critical regulator in tumor metabolism. PKM2 has been demonstrated to overexpressed in various cancers and promoted proliferation and metastasis of tumor cells.
Susi Zhu, Ye-Ye Guo, Xu Zhang, Hong Liu, Ming-Zhu Yin, Xiang Chen, C. Peng   +6 more
semanticscholar   +1 more source