Results 61 to 70 of about 1,270,348 (335)
Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]
, 2017 Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle +13 more
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Effects of Pyruvate Kinase Phosphorylation and Acetylation on Its Activity and Structure
Shipin gongye ke-jiPyruvate kinase is one of the important glycolytic enzymes that affects the rate of postmortem muscle glycolysis and then regulates meat quality.
Xiaolan HUANG +7 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 Pyruvate kinase I (PykF) is one of the key enzymes of glycolysis and plays a crucial role in bacterial metabolism. Several acetylation sites of Vibrio alginolyticus PykF were reported in previous studies and then 11 sites were first verified in this ...
Zhou Xu +17 more
doaj +1 more source
Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]
, 2015 Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk +9 more
core +1 more source
Cell Reports, 2019 Summary: Pyruvate kinase is an important enzyme in glycolysis and a key metabolic control point. We recently observed a pyruvate kinase liver isoform (PKL) phosphorylation site at S113 that correlates with insulin resistance in rats on a 3 day high-fat ...
Brandon M. Gassaway +18 more
doaj +1 more source
International Journal of Infectious Diseases, 2023 Intro: Influenza A virus, a respiratory pathogen known to manipulate various cellular metabolic processes including glycolysis. Our earlier studies demonstrated the interaction of influenza A viral structural proteins; nucleoprotein and matrix protein ...
P. Goyal, M.S. Rajala
doaj +1 more source
Incorporating expression data in metabolic modeling: a case study of lactate dehydrogenase
, 2005 Integrating biological information from different sources to understand cellular processes is an important problem in systems biology. We use data from mRNA expression arrays and chemical kinetics to formulate a metabolic model relevant to K562 ...
Akesson +47 more
core +1 more source
Probing Conformational Feature of a Recombinant Pyruvate Kinase by Limited Proteolysis [PDF]
Journal of Sciences, Islamic Republic of Iran, 2013 Pyruvate kinase is a key enzyme in glycolytic pathway that catalyzes the transphosphorylation between phosphoenolpyruvate and ADP to yield ATP and Pyruvate.
M. Banijamali +2 more
doaj
Pyruvate kinase deficiency mimicking congenital dyserythropoietic anemia type I
The Turkish Journal of Pediatrics, 2022 Background. Pyruvate kinase (PK) deficiency is the most common enzyme abnormality in the glycolytic pathway. Here, we describe two siblings with PK deficiency that mimicked congenital dyserythropoietic anemia (CDA) type I. Case.
Ayça Koca Yozgat +4 more
doaj +1 more source
Isoform switch of pyruvate kinase M1 indeed occurs but not to pyruvate kinase M2 in human tumorigenesis. [PDF]
PLoS ONE, 2015 Muscle type of pyruvate kinase (PKM) is one of the key mediators of the Warburg effect and tumor metabolism. Due to alternative splicing, there are at least 12 known isoforms of the PKM gene, of which PKM1 and PKM2 are two major isoforms with only a 23 ...
Cheng Zhan +7 more
doaj +1 more source