Results 51 to 60 of about 1,722,299 (336)
Acquired pyruvate kinase deficiency. The effect of maleic acid upon human erythrocyte pyruvate kinase [PDF]
, 1979 1. 1. Maleic acid is shown to be able to bind the thiol compound 2-mercaptoethanol. This is fully consistent with the data of Morgan and Friedman (1938). 2. 2.
Sprengers, E.D., Staal, Gerard E.J.
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Probing Conformational Feature of a Recombinant Pyruvate Kinase by Limited Proteolysis [PDF]
Journal of Sciences, Islamic Republic of Iran, 2013 Pyruvate kinase is a key enzyme in glycolytic pathway that catalyzes the transphosphorylation between phosphoenolpyruvate and ADP to yield ATP and Pyruvate.
M. Banijamali +2 more
doaj
Transcriptional Regulation of Pyruvate Dehydrogenase Kinase [PDF]
Diabetes & Metabolism Journal, 2012 The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes.
Ji Yun Jeong +3 more
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International Journal of Infectious Diseases, 2023 Intro: Influenza A virus, a respiratory pathogen known to manipulate various cellular metabolic processes including glycolysis. Our earlier studies demonstrated the interaction of influenza A viral structural proteins; nucleoprotein and matrix protein ...
P. Goyal, M.S. Rajala
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How we manage patients with pyruvate kinase deficiency
British Journal of Haematology, 2019 Novel therapies in development have brought a new focus on pyruvate kinase deficiency (PKD), the most common congenital haemolytic anaemia due to a glycolytic enzyme deficiency.
R. Grace, D. M. Layton, W. Barcellini
semanticscholar +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Frontiers in Veterinary Science, 2022 Pyruvate kinase I (PykF) is one of the key enzymes of glycolysis and plays a crucial role in bacterial metabolism. Several acetylation sites of Vibrio alginolyticus PykF were reported in previous studies and then 11 sites were first verified in this ...
Zhou Xu +17 more
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Detection of H2O2-induced changes in redox status of tumor-type pyruvate kinase（PKM2） [PDF]
, 2013 Recent studies shed light on a crucial function of M2 isoform of mammalian pyruvate kinase（PkM2）on tumor cell growth. Pyruvate kinase activity of PkM2 was shown to be negatively regulated by growth factors or reactive oxygen species（ros）.
久下, 周佐 +14 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pyruvate kinase activators in the context of erythropoiesis defects
Blood Red Cells & Iron: Pyruvate kinase activators are a promising class of small molecules that boost glycolytic flux and influence cellular energy metabolism. This review covers the development of pyruvate kinase activation as a therapeutic strategy and its impact on ...
Kevin H. M. Kuo +2 more
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