Results 221 to 230 of about 51,864 (248)

Promoting Proliferation with Nuclear Pyruvate Kinase M2

Science Signaling, 2011
Pyruvate kinase M2 interacts with nuclear β-catenin to promote cell proliferation.
openaire   +1 more source

Pyruvate Kinase M2

RCSB Protein Data Bank, 2022
openaire   +1 more source

การแสดงออกที่เพิ่มขึ้นของ Pyruvate Kinase M2 ในมะเร็งท่อนํ้าดี

วารสารวิทยาศาสตร์และเทคโนโลยี มหาวิทยาลัยมหาสารคาม, ฉบับพิเศษ,
openaire   +1 more source

Pyruvate Kinase M2 Activators Inhibit Tumor Growth

Cancer Discovery, 2012
Abstract Increased PKM2 tetramerization and pyruvate kinase activity suppress tumorigenesis.
openaire   +1 more source

Extracellular Pyruvate Kinase M2 regulates tumor angiogenesis

2014
Pyruvate kinase M2 (PKM2) has been studied for decades on its role in cancer metabolism. Recently, PKM2 is highlighted again for its new function: promoting gene transcription by acting as a protein kinase. Moreover, the PKM2 levels in patient circulation have been used as a diagnostic marker for many types of cancers.
openaire   +1 more source

Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent α-thalassaemia or β-thalassaemia: an open-label, multicentre, phase 2 study

Lancet, The, 2022
Kevin H M Kuo, Mark Layton, Ashutosh Lal
exaly  

Pyruvate Kinase M2

2016
Gopinath Prakasam, Mohammad Askandar Iqbal, Vibhor Gupta, Bhupender Kumar, Rameshwar N. K. Bamezai   +4 more
openaire   +1 more source

Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway

Cell Metabolism, 2020
Sophie L Lewandowski, Hannah Foster, Evgeniy Potapenko   +2 more
exaly  

Mitapivat versus Placebo for Pyruvate Kinase Deficiency

New England Journal of Medicine, 2022
Hanny Al-Samkari, Andreas Glenthøj, Madeleine M Verhovsek   +2 more
exaly  

Safety and Efficacy of Mitapivat in Pyruvate Kinase Deficiency

New England Journal of Medicine, 2019
Wilma Barcellini, Eduard Johannes Van Beers, Yaddanapudi Ravindranath   +2 more
exaly