Results 201 to 210 of about 25,295 (321)

GLYCOGEN FORMATION FROM PYRUVATE IN VITRO IN THE PRESENCE OF RADIOACTIVE CARBON DIOXIDE

, 1942
John M. Buchanan, A. Baird Hastings, Frances B. Nesbett   +2 more
openalex   +1 more source

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source

Transcriptional and neuroprotective effects of hexokinase-2 inhibitors administered after stroke. [PDF]

J Neuroinflammation
Won SJ, Uruk G, Mai N, Tu CL, Ogut D, Asatryan S, Mocanu E, Shon R, Kim K, Awakoaiye K, Arkelius K, Chang W, Singhal NS, Swanson RA.   +13 more
europepmc   +1 more source

PYRUVIC ACID

Journal of Biological Chemistry, 1942
Theodore E. Friedemann, Gladys E. Haugen
openaire   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Biology of Glycocalyx: The Essential Role in Maintaining Epithelial Barrier: A Mini-Review [PDF]

, 2019
Lalisang, Toar J.M.
core   +2 more sources

Dynamics of tryptophan metabolites and microbial adaptations during corn by-product fermentation in the pig gut microbiome. [PDF]

J Anim Sci Biotechnol
Toyoshi E, Watanabe M, Namai F, Yamane K, Kashima T, Ikeda-Ohtsubo W, Agista AZ, Yoshida A, Sakuma T, Fukuda I, Suzuki K, Yoshioka G, Imai Y, Tsuchida S, Nishiyama E, Shinkai H, Muneta Y, Uenishi H, Tobe R, Shirakawa H, Maekawa M, Mano N, Kitazawa H, Nishiyama K.   +23 more
europepmc   +1 more source

Pyruvate Measurement [PDF]

, 2020
openaire   +1 more source

Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses

, 2016
Xiaoli Li, Yaqing Li, Gaoyang Han, Xiaoran Li, Yasai Ji, Zhirui Fan, Yali Zhong, Jing Cao, Jing Zhao, Goscinski Mariusz, Mingzhi Zhang, Jianguo Wen, Jahn M. Nesland, Zhenhe Suo   +13 more
openalex   +2 more sources

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source