Results 101 to 110 of about 5,168,176 (315)

The disruption of JEN1 from Candida albicans impairs the transport of lactate [PDF]

, 2004
A lactate permease was biochemically identified in Candida albicans RM1000 presenting the following kinetic parameters at pH 5.0: Km 0.33 ± 0.09 mM and Vmax 0.85± 0.06 nmol s-1 mg dry wt-1.
Ansaldi M., Boeke J. D., Bojunga N., Casal M., Ca´ ssio F., Fonzi W. A., Gancedo J. M., Gerami-Nejad M., Hoffman C. S., Kaur S., Lorenz M. C., Lorenz M. C., Moosa M. W., Negredo A., Newman A., Odds F. C., Paiva S., Proft M., Sambrook J., Santos M. A., Soares-Silva I., Stewart E.   +21 more
core   +2 more sources

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Hyperglycemic effect of pyruvic acid phenylhydrazone [PDF]

Diabetologia, 1967
Pyruvic acid-phenylhydrazone has been shown, by injection into rats, to increase the blood sugar level. Hyperglycaemia started 30 min and ceased 330 min after the injection. This activity of the compound was counteracted by insulin and by tolbutamide.
openaire   +2 more sources

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi, Xin Liu, Nan Wang, Qianwen Zhang, Jianjun Gao, Canghai Guan, Yapeng Li, Chengru Yang, Shaowu Bi, Xinlei Zou, Xiangyu Zhong   +10 more
wiley   +1 more source

Relevance of electron spin dissipative processes to dynamic nuclear polarization via thermal mixing

, 2014
The available theoretical approaches aiming at describing Dynamic Nuclear spin Polarization (DNP) in solutions containing molecules of biomedical interest and paramagnetic centers are not able to model the behaviour observed upon varying the ...
Carretta, Pietro, Filibian, Marta, Rosso, Alberto, Serra, Sonia Colombo, Tedoldi, Fabio   +4 more
core   +2 more sources

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Ischaemic and metabolic treatment of hepatic tumours [PDF]

, 1988
For treatment of malignancies, physical and metabolic differences between tumour cells and host cells have guided the development of new approaches.
Ahrén, B, Bengmark, S
core   +3 more sources

Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome

Immunology, EarlyView.
Decreased fetal brain macrophages were previously reported in Ts1Cje mice, a model of Down syndrome (DS). We confirmed the reduction in primitive macrophages, brain macrophage precursors, using Ts1Cje‐derived mouse embryonic stem cells (Ts1Cje‐mESCs) and human induced pluripotent stem cells with trisomy 21 (Tri21‐hiPSCs), with in vivo validation ...
Koki Harada, Keiichi Ishihara, Sayaka Wakayama, Teruhiko Wakayama, Sae Yamamoto, Haruhiko Sago, Shun Shimohama, Satoshi Akiba, Florent Ginhoux, Kazuyuki Takata   +9 more
wiley   +1 more source

Identification of a novel link connecting indole‐3‐acetamide with abscisic acid biosynthesis and signaling

New Phytologist, EarlyView.
Summary Plants orchestrate their developmental processes and responses to environmental stimuli through a sophisticated network of small signaling molecules, termed phytohormones. Among these, auxins are recognized for their role in promoting plant growth.
José Moya‐Cuevas, Paloma Ortiz‐García, Adrián González Ortega‐Villaizán, Irene Viguera‐Leza, Andrés Pérez‐González, Javier Paz‐Ares, Carlos Alonso‐Blanco, Jesús Vicente‐Carbajosa, Stephan Pollmann   +8 more
wiley   +1 more source

Structure–Reactivity Relationships of Oxime–Oxalate/Glyoxylate/Ester Derivatives: Dual Photo/Thermal Initiators for Visible Light Polymerization and Composite Preparation

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
OP1, a newly synthesized nitro‐carbazole oxime oxalate, shows superior Type I photoinitiation under blue LEDs and sunlight due to efficient decarboxylation. It enables high‐resolution 3D printing, offers dual photo/thermal initiation, lower cytotoxicity than TPO, and provides insights for designing sustainable photoinitiators.
Tong Gao, Thybault De Monfreid, Ji Feng, Jing Zhang, Fabrice Morlet‐Savary, Céline Dietlin, Michael Schmitt, Frédéric Dumur, Jean‐Patrick Joly, Malek Nechab, Pu Xiao, Jacques Lalevée   +11 more
wiley   +2 more sources