Results 41 to 50 of about 27,119 (206)

Early Differentiation Signatures in Human Induced Pluripotent Stem Cells Determined by Non-Targeted Metabolomics Analysis

Metabolites, 2023
Human induced pluripotent stem cells (hiPSCs) possess immense potential as a valuable source for the generation of a wide variety of human cells, yet monitoring the early cell differentiation towards a specific lineage remains challenging. In this study,
Rodi Abdalkader, Romanas Chaleckis, Takuya Fujita   +2 more
doaj   +1 more source

Molecular dynamics simulations of oleuropein diffusion in chitosan‐based nanoparticles

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study explores the diffusion mechanisms of oleuropein (OLE), a promising polyphenolic compound, within chitosan‐based nanoparticles using molecular dynamics simulations. Chitosan nanoparticles serve as drug delivery carriers, leveraging biocompatibility and tunable release properties influenced by environmental factors such as ...
Bernardino Tirri, Andrea Lorenzoni, Francesco Mercuri, Pietro Calandra   +3 more
wiley   +1 more source

Identification of differential metabolites in liquid diet fermented with Bacillus subtilis using gas chromatography time of flight mass spectrometry

Animal Nutrition, 2016
Growth and health responses of pigs fed fermented liquid diet are not always consistent and causes for this issue are still not very clear. Metabolites produced at different fermentation time points should be one of the most important contributors ...
Yuyong He, Chunxia Mao, Zhiyu Chen, Hong Wen, Wei Lu, Huadong Wu   +5 more
doaj   +1 more source

Variability in Bulb Organosulfur Compounds, Sugars, Phenolics, and Pyruvate among Greek Garlic Genotypes: Association with Antioxidant Properties

Antioxidants, 2020
In order to assess the diversity of Greek garlic (Allium sativum L.) landraces, 34 genotypes including commercial ones were grown in the same field and their content in organosulfur compounds, pyruvate, total sugars, and total phenolics, alongside ...
Ioanna Avgeri, Konstantina Zeliou, Spyridon A. Petropoulos, Penelope J. Bebeli, Vasileios Papasotiropoulos, Fotini N. Lamari   +5 more
doaj   +1 more source

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

Journal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit, Marilena Vered, Michael Saminsky, Liat Chaushu   +3 more
wiley   +1 more source

HPLC Determination of α-keto Acids from Human Serum Using 2,3-Diamino-2,3-dimethylbutane as Derivatizing Reagent [PDF]

Pakistan Journal of Analytical & Environmental Chemistry, 2013
Seven α-keto acids, pyruvic acid (PYR), 2-oxobutyric acid (KB), 3-methyl-2-oxobutyric acid (MKBA), 3-methyl-2-oxovaleric acid (K3MVA), 4-methyl-2-oxovaleric acid (K4MVA), 2-oxoglutaric acid (KG) and Phenyl pyruvic acid (PPY) as derivatives of 2,3-diamino-
Khalida Parveen Mahar, Muhammad Yar Khuhawar, Kulsoom Ubedullah Abbasi, Gulam Qadir Shar, Rafia Azmat, Jameel Ahmed Baig   +5 more
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Melatonin Promotes Improvement in Serum Lipid Levels and Liver Histopathology in Hyperlipidemic Rats

Lipids, EarlyView.
ABSTRACT Hyperlipidemia or dyslipidemia is the term used for the increase in lipid levels in blood plasma, usually occurring due to a high‐fat diet associated with a sedentary lifestyle. The increase in lipid levels can cause fatty infiltration in the liver known as hepatic steatosis, which can lead to inflammation, fibrosis, and necrosis consecutively.
Ana Cláudia Carvalho de Sousa, Jaiurte Gomes Martins da Silva, Érique Ricardo Alves, Laís Caroline da Silva Santos, Bruno José do Nascimento, Marcelle Mariana Sales de França, Vanessa Bischoff Medina, Ismaela Maria Ferreira de Melo, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +9 more
wiley   +1 more source

Rehabilitation Improves Mitochondrial Energetics in Progressive Multiple Sclerosis: The Significant Role of Robot-Assisted Gait Training and of the Personalized Intensity

Diagnostics, 2020
Abnormal levels of pyruvate and lactate were reported in multiple sclerosis (MS). We studied the response of markers of mitochondrial function to rehabilitation in relation to type, intensity and endurance performance in severely disabled MS patients ...
Fabio Manfredini, Sofia Straudi, Nicola Lamberti, Simone Patergnani, Veronica Tisato, Paola Secchiero, Francesco Bernardi, Nicole Ziliotto, Giovanna Marchetti, Nino Basaglia, Massimo Bonora, Paolo Pinton   +11 more
doaj   +1 more source

Physiological Interpretation of the Lactate to Pyruvate AUC Ratio for Hyperpolarized [1‐13C]‐Pyruvate Studies

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To explore the relationship between potentially rate‐limiting steps in lactate production and the lactate area‐under‐the‐curve (AUC) to pyruvate AUC ratio for analysis of hyperpolarized (HP) [1‐13C]‐pyruvate data. Theory and Methods Simplifying assumptions are introduced to a pharmacokinetic (PK) model with three physical compartments ...
Ryan T. Boyce, Collin J. Harlan, Qing Wang, Christopher M. Walker, Stephen Y. Lai, Matthew E. Merritt, James A. Bankson   +6 more
wiley   +1 more source

Effect of curd freezing and packaging methods on the organic acid contents of goat cheeses during storage

Mljekarstvo, 2011
Effects of freezing and packaging methods on organic acid content of goat cheese during 12 weeks of storage were determined. Goat cheese milk curds were divided into two batches; one of the batches was directly processed in to goat cheese while the other
Pınar Balkir, Özlem Kizilirmak Esmer, A. Kemal Seçkin, Pelin Günç Ergönül   +3 more
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