Bactrocera dorsalis is a well-known invasive pest that causes considerable ecological and economic losses worldwild. Although it has a wide environmental tolerance, few studies have reported its mechanism of adaptation to multiple sub-lethal ...
Lili Ren +8 more
doaj +1 more source
Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub
The Warburg effect, also referred as aerobic glycolysis, is a common metabolic program during viral infection. Through targeted metabolomics combined with biochemical experiments and various cell models, we investigated the central carbon metabolism (CCM)
Guanning Su +6 more
doaj +1 more source
Cryogen-Free dissolution Dynamic Nuclear Polarization polarizer operating at 3.35 T, 6.70 T and 10.1 T [PDF]
Purpose: A novel dissolution dynamic nuclear polarization (dDNP) polarizer platform is presented. The polarizer meets a number of key requirements for in vitro, pre-clinical and clinical applications.
Ardenkjaer-Larsen, Jan Henrik +6 more
core +2 more sources
Aryl hydrocarbon receptor (AHR) agonists are promising immunomodulators that potentially maintain immune tolerance. In this study, we examined the ability of indole-3-pyruvic acid (IPA), a major precursor of microbiota-derived AHR agonists and a ...
R. Aoki +3 more
semanticscholar +1 more source
Energetics of the Citric Acid Cycle in the Deep Biosphere
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
wiley +1 more source
ω-Amino acid-pyruvate aminotransferase [PDF]
Publisher Summary ω -Amino acid-pyruvate aminotransferase ( β- alanine-pyruvate aminotransferase) was originally designated taurine-pyruvate aminotransferase and may correspond to β-alanine-pyruvate aminotransferase. The enzyme catalyzes the reversible transamination of various sulfur-containing ω-amino acids and ω-amino carboxylic acids with ...
K, Yonaha, S, Toyama, K, Soda
openaire +2 more sources
In this study performance of three drying methods on nutritional and important volatile components of red onion were evaluated. Onion (Allium cepa L.) is a strong-flavoring vegetable consumed in different ways, mainly due to its distinctive flavor or ...
AYALEW DEMISSEW +2 more
doaj +1 more source
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang +16 more
wiley +1 more source
Effect of Cephalosporin Antibiotics on the Activity of Yoghurt Cultures
The presence of antibiotics in milk is a significant problem affecting the technological safety of dairy products. The aim of the study was to determine the sensitivity of yoghurt cultures to residual levels of selected cephalosporin antibiotics ...
Pavlina Navrátilova +4 more
doaj +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source

