Results 161 to 170 of about 14,082 (237)
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
Journal of the American College of Cardiology, 2008 Molyneux, Sarah L. +6 more
openaire +2 more sources
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley +1 more source
Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights
British Journal of Pharmacology, EarlyView.Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra +5 more
wiley +1 more source
A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells
Cell Proliferation, EarlyView.This study presents a 3D bioprinted platform using gelatin‐hyaluronic acid hydrogels to enhance primary AML cell survival and proliferation while preserving stem‐like properties in vitro. By recapitulating in vivo‐like metabolic activity and drug resistance, this system offers a robust tool for preclinical drug screening and personalised therapy ...
Wanling Huang +10 more
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To systematically review the current evidence on physical therapy interventions for children and adolescents with myelomeningocele, the most complex and common presentation of spina bifida, to explore intervention components and the outcomes according to International Classification of Functioning, Disability and Health (ICF) domains, and ...
Lorena Costa Ferreira +3 more
wiley +1 more source
Diabetic Medicine, EarlyView.Abstract Aims Investigate the relationship of gestational diabetes (GDM) risk for specific migrant groups compared to the Australian born of each ethnic group and length of residence (LOR) in Australia. Methods Retrospective observational cohort study from June 2020 to November 2023 at 10 Australian hospitals.
Sheila Pham +12 more
wiley +1 more source
Dental Traumatology, EarlyView.ABSTRACT Background/Aim To assess knowledge of initial management of traumatic dental injuries among senior medical students and to compare knowledge at cohort level before and after implementation of structured teaching on traumatic dental injury management within an emergency medicine module.
Lennart Johannes Gruber +5 more
wiley +1 more source
Evaluation of Dental Trauma Knowledge and ToothSOS Application Awareness Among Emergency Physicians
Dental Traumatology, EarlyView.ABSTRACT Background/Aim Emergency physicians are among the first healthcare professionals to manage traumatic dental injuries, yet knowledge deficiencies may compromise early care. This study evaluated emergency physicians' knowledge of traumatic dental injury management, ToothSOS awareness, and factors independently associated with overall knowledge ...
Berkehan Aykanat +6 more
wiley +1 more source
Dental Traumatology, EarlyView.ABSTRACT Background/Aim Appropriate first‐aid management of traumatic dental injuries (TDIs) is highly time‐sensitive and critically influences prognosis. Parents frequently represent the first point of contact following injury. Although the ToothSOS mobile application (App) is based on current guidelines of the International Association of Dental ...
Makbule Buse Dundar Sari +2 more
wiley +1 more source