Results 21 to 30 of about 146,455 (101)
DBT affects sleep in both circadian and non-circadian neurons.
PLoS Genetics, 2022 Sleep is a very important behavior observed in almost all animals. Importantly, sleep is subject to both circadian and homeostatic regulation. The circadian rhythm determines the daily alternation of the sleep-wake cycle, while homeostasis mediates the ...
Jialin Wang +4 more
doaj +1 more source
PGK1 inhibitor CBR-470-1 protects neuronal cells from MPP+
Aging, 2020 The neurotoxin MPP+ (1-methyl-4-phenylpyridinium ion) disrupts mitochondrial function leading to oxidative stress and neuronal death. Here we examine whether activation of the Keap1-Nrf2 cascade can protect SH-SY5Y neuroblastoma cells from MPP+-induced ...
Jin-yu Zheng +6 more
semanticscholar +1 more source
Transcriptomics of Biostimulation of Plants Under Abiotic Stress
Frontiers in Genetics, 2021 Plant biostimulants are compounds, living microorganisms, or their constituent parts that alter plant development programs. The impact of biostimulants is manifested in several ways: via morphological, physiological, biochemical, epigenomic, proteomic ...
Susana González-Morales +5 more
doaj +1 more source
Frontiers in Genetics, 2021 Pathological changes in the ligamentum flavum (LF) can be defined as a process of chronic progressive aberrations in the nature and structure of ligamentous tissues characterized by increased thickness, reduced elasticity, local calcification, or ...
Baoliang Zhang +5 more
doaj +1 more source
Frontiers in Genetics, 2021 Bovine respiratory disease (BRD) causes substantial morbidity and mortality, affecting cattle of all ages. One of the main causes of BRD is an initial inflammatory response to bovine respiratory syncytial virus (BRSV).
Dayle Johnston +9 more
doaj +1 more source
Deep 230-470 MHz VLA observations of the mini-halo in the Perseus cluster [PDF]
, 2017 We present a low-frequency view of the Perseus cluster with new observations from the Karl G. Jansky Very Large Array (JVLA) at 230–470 MHz. The data reveal a multitude of new structures associated with the mini-halo. The mini-halo seems to be influenced
M. Gendron-Marsolais +8 more
semanticscholar +1 more source
Frontiers in Genetics, 2022 Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairments in social reciprocity and communication, restrictive interests, and repetitive behaviors.
Julia S. Mouat +7 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, 2018 Chronic spontaneous urticaria (CSU) is defined as spontaneous occurrence of wheals and/or angioedema for ≥6 weeks. Omalizumab is a monoclonal anti‐IgE antibody effective in refractory CSU, but its mechanism of action and markers predictive of response ...
Angelo V. Marzano +21 more
semanticscholar +1 more source
Journal of Crohn's & Colitis, 2016 BACKGROUND AND AIMS AVX-470 is an oral, polyclonal bovine-derived anti-tumour necrosis factor (TNF) antibody in development for treatment of inflammatory bowel disease (IBD).
M. Harris +9 more
semanticscholar +1 more source
Frontiers in Immunology, 2018 The allogeneic therapeutic vaccine CSF-470 has demonstrated a significant benefit over medium-dose IFNα2b in the distant metastasis-free survival for stages IIB–IIC–III cutaneous melanoma patients in a randomized phase II/III clinical trial (CASVAC-0401,
Mariana Aris +9 more
semanticscholar +1 more source