Results 111 to 120 of about 1,004,764 (341)

Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted helminths in three endemic countries

PLoS Neglected Tropical Diseases, 2019
Background Because the success of deworming programs targeting soil-transmitted helminths (STHs) is evaluated through the periodically assessment of prevalence and infection intensities, the use of the correct diagnostic method is of utmost importance ...
P. Cools, J. Vlaminck, M. Albonico, S. Ame, Mio Ayana, Barrios Perez José Antonio, G. Cringoli, D. Dana, J. Keiser, M. P. Maurelli, C. Maya, L. Matoso, A. Montresor, Z. Mekonnen, G. Mirams, R. Corrêa-Oliveira, Simone A Pinto, L. Rinaldi, S. Sayasone, Eurion Thomas, J. Verweij, J. Vercruysse, B. Levecke   +22 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]

, 2016
Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene, Fatica, Alessandro, Fazi, Francesco, Iosue', Ilaria, Larivera, Simone, Legnini, Ivano, Mangiavacchi, Arianna, Masciarelli, Silvia, Sorci, Melissa   +8 more
core   +2 more sources

RT-qPCR v1

, 2017

openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A CRY-BIC negative-feedback circuitry regulating blue light sensitivity of Arabidopsis. [PDF]

, 2017
Cryptochromes are blue light receptors that regulate various light responses in plants. Arabidopsis cryptochrome 1 (CRY1) and cryptochrome 2 (CRY2) mediate blue light inhibition of hypocotyl elongation and long-day (LD) promotion of floral initiation. It
Gu, Lianfeng, Han, Yun-Jeong, He, Wenjin, Kim, Jeong-Il, Lin, Chentao, Liu, Bin, Liu, Bobin, Liu, Qing, Matsui, Minami, Oka, Yoshito, Su, Jun, Wang, Jian, Wang, Qin, Wang, Xu, Yang, Zhaohe, Zuo, Zecheng   +15 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Monitoring bioaerosol and odour emissions from composting facilities - WR1121 [PDF]

, 2013
Government policy requires that valuable resources should be recovered and recycled from biodegradable waste. A successful and growing organics recycling industry delivers this policy with composting being one of the principal technologies deployed to ...
Al-Ashaab, Reyna, Butterfield, David, Coughlin, Toni, Drew, Gillian, Gladding, Toni, Hansell, Anna, Lamarre, Baptiste, Longhurst, Phil, Nelson, Alan, Simpson, Annika, Tyrrel, Sean, Williams, Melanie   +11 more
core  

Competitiveness of Quantitative Polymerase Chain Reaction (qPCR) and Droplet Digital Polymerase Chain Reaction (ddPCR) Technologies, with a Particular Focus on Detection of Antibiotic Resistance Genes (ARGs) [PDF]

, 2021
Solmoi Park, Anita Rana, Way Sung, Mariya Munir   +3 more
openalex   +1 more source

Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets

Nature Microbiology, 2020
C. Vogels, A. Brito, A. Wyllie, J. Fauver, I. Ott, C. Kalinich, M. Petrone, A. Casanovas-Massana, M. C. Muenker, A. Moore, J. Klein, Peiwen Lu, Alice Lu-Culligan, Xiaodong Jiang, Daniel J. Kim, Eriko Kudo, Tianyang Mao, Miyu Moriyama, Ji-Eun Oh, Annsea Park, Julio Silva, E. Song, Takehiro Takahashi, M. Taura, M. Tokuyama, A. Venkataraman, Orr-El Weizman, P. Wong, Yexin Yang, N. R. Cheemarla, Elizabeth B White, S. Lapidus, Rebecca Earnest, B. Geng, P. Vijayakumar, C. Odio, John B. Fournier, S. Bermejo, S. Farhadian, C. D. Cruz, A. Iwasaki, A. Iwasaki, A. Ko, M. Landry, E. Foxman, N. Grubaugh   +45 more
semanticscholar   +1 more source