Results 21 to 30 of about 228,793 (115)

Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis

open access: yesOncoTargets and Therapy, 2021
Background Circular RNAs (circRNAs) have been disclosed to exert important roles in human cancers, including gastric cancer (GC). CircRNA hsa_circ_0000144 was identified as an oncogene in GC development.
Haifeng Gao   +3 more
semanticscholar   +1 more source

CircNT5E promotes the proliferation and migration of bladder cancer via sponging miR-502-5p

open access: yesJournal of Cancer, 2021
Accumulating evidence suggest that circRNA RNAs (circRNAs) play important roles in tumor formation and development. circNT5E has been shown to be an oncogenic gene in several types of cancer, and the high expression of circNT5E lead to tumorigenesis and ...
Jinhui Yang   +8 more
semanticscholar   +1 more source

The spectrum and differential diagnosis of acquired ocular motor nerve palsies: a clinical study of 502 patients

open access: yesJournal of Neurology, 2021
Ocular motor nerve palsies (OMNP) frequently cause patients to present in an emergency room. In the following study, we report the differential diagnosis of OMNP by use of magnetic resonance imaging (MRI) and CSF examination as a standard. We performed a
Rebecca Hörner   +3 more
semanticscholar   +1 more source

MicroRNA miR-502-5p inhibits ovarian cancer genesis by downregulation of GINS complex subunit 2

open access: yesBioengineered, 2021
Ovarian cancer (OC) is one of the most common malignancies with high incidence and mortality and the eighth most common cancer-associated mortality in women worldwide. Aberrant expression of the GINS complex subunit 2 (GINS2) gene and miR-502-5p has been
Lili Zhan   +4 more
semanticscholar   +1 more source

MiR-502 Suppresses TNF-α-Induced Nucleus Pulposus Cell Apoptosis by Targeting TARF2

open access: yesBioMed Research International, 2021
Intervertebral disc degeneration (IVDD) is a common cause of low back pain. This study is aimed at investigating the role of microRNAs (miRNAs) in regulating human nucleus pulposus (NP) cell injury induced by tumor necrosis factor- (TNF-) α in IVDD.
Zhao Guo   +5 more
semanticscholar   +1 more source

Hsa_circ_0032131 knockdown inhibits osteoarthritis progression via the miR-502-5p/PRDX3 axis

open access: yesAging, 2021
Osteoarthritis (OA) is a chronic disease characterized by progressive loss of cartilage and failure of the diarthrodial joint. Circular RNAs (circRNAs) are known to participate in the pathogenesis of multiple diseases, including OA.
Jin Xu, Xinlong Ma
semanticscholar   +1 more source

MicroRNA-502-3p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1

open access: yesMolecular Medicine Reports, 2021
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tuberculosis) infection and has the highest mortality rate of any single infectious disease worldwide.
Fang Liu   +5 more
semanticscholar   +1 more source

CCND1, NOP14 and DNMT3B are involved in miR‐502‐5p–mediated inhibition of cell migration and proliferation in bladder cancer

open access: yesCell Proliferation, 2020
Downregulation of miR‐502‐5p has emerged as a critical factor in tumour progression in several cancers. Herein, we elucidated the role of miR‐502‐5p in bladder cancer.
Yufan Ying   +13 more
semanticscholar   +1 more source

MicroRNA-502-3p regulates GABAergic synapse function in hippocampal neurons

open access: yesNeural Regeneration Research
JOURNAL/nrgr/04.03/01300535-202412000-00026/figure1/v/2024-04-08T165401Z/r/image-tiff Gamma-aminobutyric acid (GABA)ergic neurons, the most abundant inhibitory neurons in the human brain, have been found to be reduced in many neurological disorders ...
Bhupender Sharma   +4 more
semanticscholar   +1 more source

Cytosolic DNA sensors activation of human astrocytes inhibits herpes simplex virus through IRF1 induction

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionWhile astrocytes participate in the CNS innate immunity against herpes simplex virus type 1 (HSV-1) infection, they are the major target for the virus.
Yu Liu   +9 more
doaj   +1 more source

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