Results 21 to 30 of about 216,418 (115)

CircNT5E promotes the proliferation and migration of bladder cancer via sponging miR-502-5p

open access: yesJournal of Cancer, 2021
Accumulating evidence suggest that circRNA RNAs (circRNAs) play important roles in tumor formation and development. circNT5E has been shown to be an oncogenic gene in several types of cancer, and the high expression of circNT5E lead to tumorigenesis and ...
Jinhui Yang   +8 more
semanticscholar   +1 more source

Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis

open access: yesOncoTargets and Therapy, 2021
Background Circular RNAs (circRNAs) have been disclosed to exert important roles in human cancers, including gastric cancer (GC). CircRNA hsa_circ_0000144 was identified as an oncogene in GC development.
Haifeng Gao   +3 more
semanticscholar   +1 more source

MicroRNA miR-502-5p inhibits ovarian cancer genesis by downregulation of GINS complex subunit 2

open access: yesBioengineered, 2021
Ovarian cancer (OC) is one of the most common malignancies with high incidence and mortality and the eighth most common cancer-associated mortality in women worldwide. Aberrant expression of the GINS complex subunit 2 (GINS2) gene and miR-502-5p has been
Lili Zhan   +4 more
semanticscholar   +1 more source

MiR-502 Suppresses TNF-α-Induced Nucleus Pulposus Cell Apoptosis by Targeting TARF2

open access: yesBioMed Research International, 2021
Intervertebral disc degeneration (IVDD) is a common cause of low back pain. This study is aimed at investigating the role of microRNAs (miRNAs) in regulating human nucleus pulposus (NP) cell injury induced by tumor necrosis factor- (TNF-) α in IVDD.
Zhao Guo   +5 more
semanticscholar   +1 more source

Hsa_circ_0032131 knockdown inhibits osteoarthritis progression via the miR-502-5p/PRDX3 axis

open access: yesAging, 2021
Osteoarthritis (OA) is a chronic disease characterized by progressive loss of cartilage and failure of the diarthrodial joint. Circular RNAs (circRNAs) are known to participate in the pathogenesis of multiple diseases, including OA.
Jin Xu, Xinlong Ma
semanticscholar   +1 more source

MicroRNA-502-3p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1

open access: yesMolecular Medicine Reports, 2021
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tuberculosis) infection and has the highest mortality rate of any single infectious disease worldwide.
Fang Liu   +5 more
semanticscholar   +1 more source

CCND1, NOP14 and DNMT3B are involved in miR‐502‐5p–mediated inhibition of cell migration and proliferation in bladder cancer

open access: yesCell Proliferation, 2020
Downregulation of miR‐502‐5p has emerged as a critical factor in tumour progression in several cancers. Herein, we elucidated the role of miR‐502‐5p in bladder cancer.
Yufan Ying   +13 more
semanticscholar   +1 more source

Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report

open access: yesFrontiers in Microbiology, 2018
Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with ATL and inflammatory diseases but remains a neglected health problem. HTLV-1 associated diseases were originally described as sporadic entities, but family aggregations have been ...
Antonio C. R. Vallinoto   +7 more
doaj   +1 more source

Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB ...
Ranjeet Kumar   +5 more
doaj   +1 more source

Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces

open access: yesFrontiers in Microbiology
IntroductionInflammation and oxidative stress can seriously endanger the health and growth of beef cattle. Scutellaria baicalensis Georgi (SB) has significant anti-inflammatory and antioxidative effects.
Junli Zhang   +5 more
doaj   +1 more source

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