Results 141 to 150 of about 1,617,447 (322)

miRNA profiling in autism spectrum disorder in China

Genomics Data, 2015
Autism spectrum disorder (ASD) is a clinically complex and heterogeneous disorder. It is characterized by impaired social abilities, disordered language, isolated areas of interest, and repetitive behaviors.
Fengzhen Huang, Tieqiao Zhou, Xiaoxi Yao, Jiping Yi, Fei Zhou, Zhe long, Xuan Hou, Chunrong Wang, Zhao Chen, Hong Jiang   +9 more
doaj   +1 more source

Quantification of long non-coding RNAs using qRT-PCR: comparison of different cDNA synthesis methods and RNA stability

Archives of medical science : AMS, 2019
Introduction Long non-coding RNAs (lncRNAs), a class of regulatory RNA molecules, are over 200 nucleotides long and could be used as a new potential biomarker, but their detection methods such as qRT-PCR are still not validated, and the influence of RNA ...
Tomasz Kolenda, Marcel Ryś, Kacper Guglas, Anna Teresiak, Renata Bliźniak, J. Mackiewicz, K. Lamperska   +6 more
semanticscholar   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

GENE EXPRESSION of blaOXA-51-like and blaOXA-23 in RESPONSE to β-Lactam ANTIBIOTIC IN CLINICALLY ISOLATED ACINETOBACTER BAUMANNII AND ACINETOBACTER LOWFFII FROM URINE SAMPLES

The Iraqi Journal of Agricultural science, 2019
In this study, two isolates A. lowffii, and A. baumannii were obtained clinically, and genomically identified by 16S rRNA assessment with the accession number (MH685113.1 and MH685112.1) for A. lowffii and A. baumannii respectively.
H. H. Al-Haideri
doaj   +1 more source

Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]

, 2017
BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi, Bittmann, Claire Crossan, Clemenceau, Clemenceau, Cooper, Denner, Denner, Denner, Dieckhoff, Fishman, Gazda, Guo, Irgang, Kimsa, Korbutt, Linda Scobie, Matsumoto, Mazurek, Moon, Morozov, Mourad, Mueller, Nizar I. Mourad, Patience, Pierre Gianello, Pizzato, Schuurman, Scobie, Spizzo, Sypniewski, Tacke, Tucker, Victoria Cruikshank, Wynyard, Wynyard, Zhang   +36 more
core   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Profiles of circulating miRNAs following metformin treatment in patients with type 2 diabetes [PDF]

Journal of Medical Biochemistry, 2018
Background: Metformin, a widely used biguanide class of anti-diabetic drug, has potential to increase insulin sensitivity and reduce blood glucose to treat type 2 diabetes (T2D). It has been reported that metformin has an activity on regulation of miRNAs
Halil Demirsoy İbrahim, Yolal Ertural Duygu, Balci Şenay, Çinkir Ümit, Sezer Kerem, Tamer Lülüfer, Aras Nurcan   +6 more
doaj  

Seroprevalence of Zika virus in wild African green monkeys and baboons [PDF]

, 2017
Zika virus (ZIKV) has recently spread through the Americas and has been associated with a range of health effects, including birth defects in children born to women infected during pregnancy. Although the natural reservoir of ZIKV remains poorly defined,
Adam L. Bailey, Andrea M. Weiler, Anna J. Jasinska, Clifford J. Jolly, Connor R. Buechler, Cristian Apetrei, David H. O’Connor, Gabrielle L. Barry, Jane E. Phillips-Conroy, Jeffrey Rogers, John Schoggins, Laurel M. Stewart, Meghan E. Breitbach, Nelson B. Freimer, Thomas C. Friedrich   +14 more
core   +3 more sources

Selection and validation of reference genes desirable for gene expression analysis by qRT-PCR in MeJA-treated ginseng hairy roots

PLoS ONE, 2019
Ginseng is a valuable herb of traditional Chinese medicine and ginsenosides, the main bioactive components of ginseng, have been proven to have multiple functions in human therapies and health.
Li Li, Kangyu Wang, Mingzhu Zhao, Shaokun Li, Yue Jiang, Lei Zhu, Jing Chen, Yanfang Wang, Chun-yu Sun, Ping Chen, Jun Lei, Mei‐Ling Zhang, Yi Wang   +12 more
semanticscholar   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source