Results 61 to 70 of about 157,946 (333)
Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]
, 2004 Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K. +4 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]
, 2015 Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core +1 more source
Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. [PDF]
, 2015 Genome-wide association studies have identified over 70 single-nucleotide polymorphisms (SNPs) associated with breast cancer. A subset of these SNPs are associated with quantitative expression of nearby genes, but the functional effects of the majority ...
Brenner, Steven E +8 more
core +2 more sources
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
Advanced Science, EarlyView.A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Electronic Journal of Plant Breeding, 2020 Drought is one of the major constraints affecting rice (Oryza sativa L.) productivity and production. Conventional breeding is leading to slow progress in developing drought tolerant varieties.
Krishna Sai Karnatam, Deepa Jaganathan, Kambale Rohit Dilip, Manikanda Boopathi N and Raveendran Muthurajan
doaj +1 more source
Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses [PDF]
, 2012 Peer reviewedPublisher ...
Blizard, David A +6 more
core +2 more sources
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
Advanced Science, EarlyView.This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source
Validated markers for sunflower (Helianthus annuus L.) breeding
Oilseeds and fats, crops and lipids, 2020 Sunflower is native to North America and is now grown around the world for edible oil, seed roasting, confectionary products and bird food. Genetic diversity in cultivated and wild germplasm is characterized for use with various breeding objectives ...
Rauf Saeed +3 more
doaj +1 more source
Detection of quantitative trait loci for locomotion and osteochondrosis-related traits in Large White x Meishan pigs. [PDF]
, 2003 Data from the F2 generation of a Large White (LW) 5 Meishan (MS) crossbred population were analysed to detect quantitative trait loci (QTL) for leg and gait scores, osteochondrosis and physis scores.
Archibald, Alan +6 more
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