Results 171 to 180 of about 25,499,012 (214)

Association mapping and genome prediction reveal a complex genetic architecture for resistance to black and frosty pod rot in cacao (Theobroma cacao L.) populations

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Cacao (Theobroma cacao L.) production is severely constrained by black pod rot (BPR) and frosty pod rot (FPR), two major diseases that cause substantial yield losses across the tropics. Breeding for disease resistance remains challenging due to long generation intervals and the complex genetic control of disease responses. Here, we used genome‐
Elisa Jacquotte, James A. Holzwarth, Ana Zotta Mota, Mariela E. Leandro‐Muñoz, Bénédicte Rhoné, Evelyn T. Todd, Maud Lepelley, Laurence Bellanger, Patrick Descombes, Fabrizio Arigoni, Audrey Fillodeau, Eduardo Beche   +11 more
wiley   +1 more source

Genomic prediction of single cross families of perennial ryegrass under two nitrogen managements

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract The performance of a single cross is determined by the additive effects of the parents and their interactions, which can be estimated through general combining ability (GCA) and specific combining ability (SCA). With genome‐wide marker information, it is possible to predict GCA for new parents and the genetic value of unrealized crosses ...
Divino Rosa dos Santos Junior, Dario Fè, Ingo Lenk, Christian S. Jensen, Torben Asp, Luc Janss, Elesandro Bornhofen   +6 more
wiley   +1 more source

Enhanced disease resistance in chickpea and canola via MAGPIE: Major‐Effect Allele and Genomic Polygenic Integration for Enhancement

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract The global agricultural industry suffers major economic losses due to fungal diseases. Though selective breeding and introgression of resistance genes with major effects have helped to reduce the impact of these diseases, resistance breakdown occurs within a few generations.
Zibei Lin, Irene van den Berg, Shahin Yazdifar, Shimna Sudheesh, Adnan Riaz, Denise Barbulescu, Yongjun Li, Kristy Hobson, Muhammad Ahsan Asif, Matthew Hayden, Sukhjiwan Kaur   +10 more
wiley   +1 more source

A chromosome‐level genome assembly of an elite indica breeding line resolves the genomic architecture of drought‐yield QTLs qDTY2.2 and qDTY4.1 in rice

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Drought‐yield quantitative trait loci (QTLs) qDTY2.2 and qDTY4.1 improve grain yield under reproductive‐stage drought in rice (Oryza sativa L.), yet their genomic architecture remains poorly resolved in elite indica breeding backgrounds. We generated a chromosome‐level assembly of IR87707‐446‐B‐B‐B (IR64‐qDTY2.2 + qDTY4.1), which carries both ...
Jae‐Hyuk Han, Na‐Hyun Shin, Keunpyo Lee, Yohei Koide, Yeisoo Yu, Il‐Ryong Choi, Joong Hyoun Chin   +6 more
wiley   +1 more source

Multi‐Omics Mendelian Randomization Prioritizes Candidate Druggable Genes for Major Depressive Disorder

Genes, Brain and Behavior, Volume 25, Issue 6, December 2026.
A multi‐omics Mendelian randomization framework integrating blood and brain eQTL/pQTL data with FinnGen GWAS identified six druggable genes causally associated with major depressive disorder. Colocalization and phenome‐wide analyses supported shared genetic architecture and safety profiles, highlighting immune‐inflammatory pathways as promising ...
Huijing Zhou, Qiang Liu, Hao Yan, Guixiang Jin, Wei Zhou, Xiaomin Yin, Nai Wang, Minhui Zheng, Haihong Zheng, Yiming Wu   +9 more
wiley   +1 more source

Harnessing genetic variation for grain quality from diverse wheat landraces

New Phytologist, Volume 252, Issue 5, Page 1924-1942, December 2026.
Grain protein content is usually measured on bulk samples, hiding variation between individual grains. We used hyperspectral imaging to predict protein in c. 15 000 single grains from over 500 Watkins wheat landraces grown in two environments, resolving both mean protein content and grain‐to‐grain uniformity.
Luqman B. Safdar, M. John Foulkes, Alix Cornish, Elizabeth D. Goodman, Andrew B. Riche, David Steele, Charlie Philp, Shiva Rahimitanha, Martin Whitworth, Iain R. Searle, Matt Kerton, Malcolm J. Hawkesford, Simon Griffiths, Rahul A. Bhosale, Scott A. Boden, Ian D. Fisk   +15 more
wiley   +1 more source

Revealing the Key Genetic Basis of Late Leaf Spot Resistance in Peanut by Combining QTL Mapping, QTL‐seq and RNA‐seq

Plant, Cell &Environment, Volume 49, Issue 12, Page 10442-10455, December 2026.
ABSTRACT Late leaf spot (LLS) is the most widespread and destructive fungal disease affecting peanut worldwide, yet relatively little is known about its genetic basis. In this study, QTL mapping using a 1327‐bin map (derived from 9533 SNP/InDel markers) and multi‐environment phenotypic data repeatedly detected two major LLS‐resistance QTLs on ...
Wenhui Cui, Pengxia Guo, Bolun Yu, Huifang Jiang, Yong Lei, Boshou Liao, Huaiyong Luo, Xin Wang, Li Huang, Nian Liu, Jianbing Guo, Weigang Chen, Xiaojing Zhou   +12 more
wiley   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3716-3732, November 2026.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Impacts of soybean breeding on shoot architecture

Crop Science, Volume 66, Issue 6, November/December 2026.
Abstract Despite decades of steady soybean (Glycine max (L.) Merr.) yield increases from improved cultivars, the accompanying changes in shoot architectural traits have been under‐researched. To address this, we analyzed 55 cultivars spanning eight decades of breeding and estimated a genetic gain for yield of 20.7 kg ha−1 year−1 in south‐central ...
Suma Sreekanta, Lovepreet Singh, Kamaldeep S. Virdi, Robert M. Stupar, Gary J. Muehlbauer, Aaron J. Lorenz   +5 more
wiley   +1 more source