Results 191 to 200 of about 29,743 (315)

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang   +9 more
wiley   +1 more source

Leading the Pack: Next‐Generation Batteries for Humanoid Robotics

open access: yesAdvanced Science, EarlyView.
Humanoid robots challenge traditional and anticipated energy technologies. Humanoid robot benchmarks of runtimes and energy demands for industry applications inform humanoid robot battery design choices at the cell level, pack level, and system level.
Matthew Bergschneider   +6 more
wiley   +1 more source

Selective Delivery of Anticancer Natural G-Quadruplex Ligands by the AT11 Aptamer for Gastric Cancer Treatment. [PDF]

open access: yesJ Med Chem
Platella C   +8 more
europepmc   +1 more source

Quadruplex Nucleic Acids as Novel Therapeutic Targets.

open access: yesJournal of Medicinal Chemistry, 2016
S. Neidle
semanticscholar   +1 more source

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

open access: yesAdvanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan   +5 more
wiley   +1 more source

Non-B DNA structures and their contributions to genetic diversity, aging, and disease. [PDF]

open access: yesNucleic Acids Res
Bochalis E   +5 more
europepmc   +1 more source

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome

open access: yesNature Methods, 2016
C. Kwok   +4 more
semanticscholar   +1 more source

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