Results 231 to 240 of about 39,485 (293)

Mechanistic study of <i>TFE3</i> breakage in <i>TFE3</i>-rearranged renal cell carcinoma: the perspective of non-canonical DNA structures and their stability. [PDF]

Front Genet
Zhang X, Dang Q, Pan X, Deng Z, Xu Y, Gan W, Guo H.   +6 more
europepmc   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source

Computational Analysis Uncovering Contrasts in G-Quadruplex Propensity and Aptamer Enrichment in SELEX-Derived Libraries. [PDF]

Chembiochem
Liu G, Wu TY, Kwok CK, Liu J.
europepmc   +1 more source

Direct Observation of Electric‐Field‐Driven Phase Transitions Associated with Energy Storage in Antiferroelectric Films

Advanced Science, EarlyView.
The electric‐field‐driven antiferroelectric‐to‐ferroelectric phase transition in epitaxial PbZrO3 films is directly visualized by in situ aberration‐corrected scanning transmission electron microscopy. A sequential transition pathway involving an orthorhombic ferrielectric phase and a monoclinic ferroelectric phase, ultimately stabilizing into a ...
Yan‐Peng Feng, Mei‐Xiong Zhu, Ru‐Jian Jiang, Yu‐Jia Wang, Yun‐Long Tang, Yin‐Lian Zhu, Xiu‐Liang Ma   +6 more
wiley   +1 more source

Aptamer-Based Dual-Cascade Signal Amplification System Lights up G-Quadruplex Dimers for Ultrasensitive Detection of Domoic Acid. [PDF]

Mar Drugs
Li J, Xu Z, Zhang Z, Liu R, Zhu Y, Lu X, Xu H, Liu X, Ning Z, Wang X, Yu H, Hu B.   +11 more
europepmc   +1 more source

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Advanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao, Shan Qiao, Jie Bai, Jingjing Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu   +10 more
wiley   +1 more source

Multiformity of a G/C Rich Segment at the Promoter-UTR Intersection of <i>RAP2C</i> Gene: Structural Validation by Circular Dichroism. [PDF]

ACS Omega
Singh A, Kukreti S.
europepmc   +1 more source

Hidden Charge‐Order in the Mixed‐Valent K0.75Li2Cr6O12 High‐Pressure Oxide

Advanced Science, EarlyView.
K0.75Li2Cr6O12 is one of the few mixed valent chromium oxides. It shows a single angle spiral magnetic structure with a k = [1/3 1/3 ¼] propagation vector. Density functional theory reveals a hidden charge order that is necessary to stabilize the antiferromagnetic (AFM) ground state.
Angel M. Arévalo‐López, Clemens Ritter, Marielle Huvé, Olivier Mentré   +3 more
wiley   +1 more source

Vincristine Beyond Mitosis: Uncovering a First Link to G-Quadruplex DNA in Cancer Cells. [PDF]

Int J Mol Sci
Di Porzio A, Persico C, Romano F, Barra A, Aiello I, D'Auria L, Abate S, D'Aria F, Giancola C, Cinquegrana E, Di Leva FS, Amato J, Marzano S, Iaccarino N, Randazzo A.   +14 more
europepmc   +1 more source